Overview

  • Product nameAnti-ABCB5 antibody
    See all ABCB5 primary antibodies
  • Description
    Rabbit polyclonal to ABCB5
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide selected from the N terminal region of human ABCB5

  • Positive control
    • K562 cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab80108 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/50 - 1/100. Predicted molecular weight: 90 kDa.

Target

  • FunctionPlasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Responsible for the resistance to doxorubicin of a subset of malignant melanomas.
  • Tissue specificityExpressed by CD133-expressing progenitor cells among epidermal melanocytes (at protein level). Widely expressed with specific expression in pigment cells. Also expressed in several malignant tissues.
  • Sequence similaritiesBelongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
    Contains 1 ABC transmembrane type-1 domain.
    Contains 2 ABC transporter domains.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ABCB 5 antibody
    • ABCB5 antibody
    • ABCB5 P-gp antibody
    • ABCB5_HUMAN antibody
    • ABCB5alpha antibody
    • ABCB5beta antibody
    • ATP binding cassette protein antibody
    • ATP binding cassette sub family B (MDR/TAP) member 5 antibody
    • ATP binding cassette sub family B member 5 antibody
    • ATP-binding cassette sub-family B member 5 antibody
    • EST422562 antibody
    • P glycoprotein ABCB5 antibody
    • P-glycoprotein ABCB5 antibody
    see all

Anti-ABCB5 antibody images

  • Anti-ABCB5 antibody (ab80108) at 1/50 dilution + K562 cell line lysates at 35 µg

    Predicted band size : 90 kDa
    Observed band size : 90 kDa

References for Anti-ABCB5 antibody (ab80108)

ab80108 has not yet been referenced specifically in any publications.

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The immunogen sequence is in both the beta and full length version of the gene. It will therefore recognize both versions of the gene.
Ab80108 antibody is generated from rabbits immunized with a KLH conjugated syn...

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