Overview

  • Product nameAnti-ABCB7 antibody
    See all ABCB7 primary antibodies
  • Description
    Rabbit polyclonal to ABCB7
  • SpecificityThis antibody reacts with ABCB7
  • Tested applicationsSuitable for: IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human ABCB7 aa 733-747 conjugated to Keyhole Limpet Haemocyanin (KLH).

  • Positive control
    • Thymus tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab65149 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml.
ELISA 1/10 - 1/1000.

Target

  • FunctionCould be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.
  • Involvement in diseaseDefects in ABCB7 are the cause of X-linked sideroblastic anemia with ataxia (ASAT) [MIM:301310]. ASAT is a recessive disorder characterized by an infantile to early childhood onset of nonprogressive cerebellar ataxia and mild anemia with hypochromia and microcytosis.
  • Sequence similaritiesBelongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
    Contains 1 ABC transmembrane type-1 domain.
    Contains 1 ABC transporter domain.
  • Cellular localizationMitochondrion inner membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ABC transporter 7 protein antibody
    • ABC7 antibody
    • Abcb7 antibody
    • ABCB7_HUMAN antibody
    • ASAT antibody
    • Atm1p antibody
    • ATP binding cassette 7 antibody
    • ATP binding cassette sub family B (MDR/TAP) member 7 antibody
    • ATP binding cassette sub family B member 7 antibody
    • ATP binding cassette sub family B member 7 mitochondrial antibody
    • ATP binding cassette transporter 7 antibody
    • ATP-binding cassette sub-family B member 7 antibody
    • ATP-binding cassette transporter 7 antibody
    • EST140535 antibody
    • MDR7 antibody
    • mitochondrial antibody
    • Multidrug resistance protein 7 antibody
    • P-glycoprotein 7 antibody
    • PGP7 antibody
    see all

Anti-ABCB7 antibody images

  • ab65149 at 10µg/ml staining ABCB7 in Formalin-Fixed Paraffin-Embedded human thymus tissue.

References for Anti-ABCB7 antibody (ab65149)

ab65149 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab65149.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"