Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab91451 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
WB
IHC-Fr
ICC
  • Application notes
    Flow Cyt: Use at an assay dependent dilution.
    ICC (acetone fixed cytospin preparations): 1/20 - 1/50.
    IHC-Fr: 1/20.
    WB: 1/20 - 1/50. Predicted molecular weight: 162 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.
    • Tissue specificity
      Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed.
    • Sequence similarities
      Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
      Contains 2 ABC transmembrane type-1 domains.
      Contains 2 ABC transporter domains.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • ABCC10 antibody
      • ATP binding cassette, sub family C (CFTR/MRP), member 10 antibody
      • ATP binding cassette, subfamily C, member 10 antibody
      • ATP-binding cassette sub-family C member 10 antibody
      • EST182763 antibody
      • mFLJ00002 antibody
      • MRP7 antibody
      • MRP7_HUMAN antibody
      • Multidrug resistance associated protein 7 antibody
      • Multidrug resistance-associated protein 7 antibody
      • SIMRP7 antibody
      see all

    Anti-ABCC10 antibody [M7I-3] images

    • ab91451 at 1/20 dilution staining ABCC10 in ABCC10 transfected HEK cells by Immunocytochemistry.

    References for Anti-ABCC10 antibody [M7I-3] (ab91451)

    This product has been referenced in:
    • De Souza R  et al. Chemotherapy dosing schedule influences drug resistance development in ovarian cancer. Mol Cancer Ther 10:1289-99 (2011). WB ; Mouse . Read more (PubMed: 21551263) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab91451.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up