Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab91451 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
WB
IHC-Fr
ICC
  • Application notes
    Flow Cyt: Use at an assay dependent dilution.
    ICC (acetone fixed cytospin preparations): 1/20 - 1/50.
    IHC-Fr: 1/20.
    WB: 1/20 - 1/50. Predicted molecular weight: 162 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.
    • Tissue specificity
      Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed.
    • Sequence similarities
      Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
      Contains 2 ABC transmembrane type-1 domains.
      Contains 2 ABC transporter domains.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • ABCC10 antibody
      • ATP binding cassette, sub family C (CFTR/MRP), member 10 antibody
      • ATP binding cassette, subfamily C, member 10 antibody
      • ATP-binding cassette sub-family C member 10 antibody
      • EST182763 antibody
      • mFLJ00002 antibody
      • MRP7 antibody
      • MRP7_HUMAN antibody
      • Multidrug resistance associated protein 7 antibody
      • Multidrug resistance-associated protein 7 antibody
      • SIMRP7 antibody
      see all

    Images

    • ab91451 at 1/20 dilution staining ABCC10 in ABCC10 transfected HEK cells by Immunocytochemistry.

    References

    This product has been referenced in:
    • De Souza R  et al. Chemotherapy dosing schedule influences drug resistance development in ovarian cancer. Mol Cancer Ther 10:1289-99 (2011). WB ; Mouse . Read more (PubMed: 21551263) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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