Overview

  • Product nameAnti-ABCC11 antibody
    See all ABCC11 primary antibodies
  • Description
    Mouse monoclonal to ABCC11
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human, Chimpanzee, Rhesus monkey
  • Immunogen

    Recombinant fragment: FVPIAVKGLT NSKSAVMRFK KFFLQESPVF YVQTLQDPSK ALVFEEATLS WQQTCPGIVN GALELERNGH ASEGMTRPRD ALGPEEEGNS LGPELHKINL, corresponding to amino acids 433-533 of Human ABCC11 (NP_115972) with tag.

  • Positive control
    • Recombinant tagged human ABCC11 fragment.

Properties

Applications

Our Abpromise guarantee covers the use of ab76727 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notesELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 154 kDa.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceABCC11 belongs to the ABC transporter family, conjugate transporter (TC 3.A.1.208) subfamily. It contains two ABC transmembrane type-1 domains and two ABC transporter domains. ABCC11 participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides and enhances the cellular extrusion of cAMP and cGMP. It also stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate. It probably functions to secrete earwax.
    • Cellular localizationMembrane; Multi-pass membrane protein.
    • Database links
    • Alternative names
      • ABCC 11 antibody
      • ATP binding cassette protein C11 antibody
      • ATP binding cassette sub family C (CFTR/MRP) member 11 antibody
      • ATP binding cassette sub family C member 11 antibody
      • ATP binding cassette transporter MRP8 antibody
      • ATP binding cassette transporter sub family C member 11 antibody
      • EWWD antibody
      • MRP8 antibody
      • Multi resistance protein 8 antibody
      • Multidrug resistance associated protein 8 antibody
      • OTTHUMP00000164191 antibody
      • WW antibody
      see all

    Anti-ABCC11 antibody images

    • Anti-ABCC11 antibody (ab76727) at 1 µg/ml + Recombinant tagged human ABCC11 fragment at 0.1 µg

      Secondary
      Goat anti-mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

      Predicted band size : 154 kDa
      Observed band size : 37 kDa (why is the actual band size different from the predicted?)

    References for Anti-ABCC11 antibody (ab76727)

    ab76727 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab76727.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"