Overview

  • Product nameAnti-ABCC11 antibody
    See all ABCC11 primary antibodies
  • Description
    Rabbit polyclonal to ABCC11
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Saccharomyces cerevisiae
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 1295-1344 (NSKIILIDEA TASIDMETDT LIQRTIREAF QGCTVLVIAH RVTTVLNCDH) of Human ABCC11 (NP_149163).

  • Positive control
    • NCI-H226 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab98979 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 154 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • RelevanceABCC11 belongs to the ABC transporter family, conjugate transporter (TC 3.A.1.208) subfamily. It contains two ABC transmembrane type-1 domains and two ABC transporter domains. ABCC11 participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides and enhances the cellular extrusion of cAMP and cGMP. It also stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate. It probably functions to secrete earwax.
  • Cellular localizationMembrane; Multi-pass membrane protein.
  • Database links
  • Alternative names
    • ABCC 11 antibody
    • ATP binding cassette protein C11 antibody
    • ATP binding cassette sub family C (CFTR/MRP) member 11 antibody
    • ATP binding cassette sub family C member 11 antibody
    • ATP binding cassette transporter MRP8 antibody
    • ATP binding cassette transporter sub family C member 11 antibody
    • EWWD antibody
    • MRP8 antibody
    • Multi resistance protein 8 antibody
    • Multidrug resistance associated protein 8 antibody
    • OTTHUMP00000164191 antibody
    • WW antibody
    see all

Anti-ABCC11 antibody images

  • Anti-ABCC11 antibody (ab98979) at 1 µg/ml + NCI-H226 cell lysate at 10 µg

    Predicted band size : 154 kDa

References for Anti-ABCC11 antibody (ab98979)

ab98979 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"