Overview

  • Product nameAnti-ABCC13 antibody
  • Description
    Rabbit polyclonal to ABCC13
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from the internal region of human ABCC13

  • Positive control
    • Human liver carcinoma tissue; extracts from 293, COLO or HT-29 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab74207 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 31 kDa.
ELISA 1/40000.
IHC-P 1/50 - 1/100.

Target

  • RelevanceThis gene is a member of the superfamily of genes encoding ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This family member is part of the MRP subfamily, which is involved in multi drug resistance, but the human locus is now thought to be a pseudogene incapable of encoding a functional ABC protein. It is expressed at its highest level in fetal liver and fetal spleen. In the adult, highest levels are found in the colon ascending and transverse. Also expressed in brain, placenta, lung, liver, pancreas and ovary. In bone marrow cells, levels are several fold higher than in peripheral blood leukocytes. There are five named isoforms.
  • Cellular localizationNucleus; integral to membrane.
  • Database links
  • Alternative names
    • ATP binding cassette protein C13 antibody
    • ATP binding cassette, sub family C (CFTR/MRP), member 13 antibody
    • C21orf73 antibody
    • PRED6 antibody

Anti-ABCC13 antibody images

  • All lanes : Anti-ABCC13 antibody (ab74207) at 1/500 dilution

    Lane 1 : Extracts from 293 cells
    Lane 2 : Extracts from COLO cells
    Lane 3 : Extracts from HT-29 cells
    Lane 4 : Extracts from 293 cells with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 31 kDa
    Observed band size : 31 kDa
  • Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using ab74207 at a 1/50 dilution.
    Left panel: not pre-treated.
    Right panel: pre-treated with immunizing peptide.

References for Anti-ABCC13 antibody (ab74207)

ab74207 has not yet been referenced specifically in any publications.

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The amino acid range of this immunogen is aa50-100 of human ABCC13 with ACC# Q9NSE7 (http://www.uniprot.org/uniprot/Q9NSE7). This antibody binds to isoforms 1, 2, 3, 4, and 5.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"