Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab117997 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/4000. Predicted molecular weight: 67 kDa.

Target

  • FunctionAntagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.
  • Sequence similaritiesBelongs to the ABC transporter superfamily. ABCE family.
    Contains 2 4Fe-4S ferredoxin-type domains.
    Contains 2 ABC transporter domains.
  • Cellular localizationCytoplasm. Mitochondrion. Localized to clusters of virus formation at the plasma membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2' 5' oligoadenylate binding protein antibody
    • 2''-5''-oligoadenylate-binding protein antibody
    • 2'5' oligoadenylate binding protein antibody
    • ABC 38 antibody
    • ABC38 antibody
    • ABCE 1 antibody
    • ABCE1 antibody
    • ABCE1_HUMAN antibody
    • ATP binding cassette sub family E (OABP) member 1 antibody
    • ATP binding cassette sub family E member 1 antibody
    • ATP-binding cassette sub-family E member 1 antibody
    • HuHP 68 antibody
    • HuHP68 antibody
    • OABP antibody
    • Ribonuclease 4 inhibitor antibody
    • Ribonuclease L (2' 5' oligoisoadenylate synthetase dependent) inhibitor antibody
    • Ribonuclease L (2'5' oligoisoadenylate synthetase dependent) inhibitor antibody
    • Ribonuclease L inhibitor antibody
    • RLI antibody
    • RNase L inhibitor antibody
    • RNASEL1 antibody
    • RNASELI antibody
    • RNS 4I antibody
    • RNS4I antibody
    see all

Anti-ABCE1 antibody images

  • Anti-ABCE1 antibody (ab117997) at 1/2000 dilution + Hela cells at 65 µg
    Developed using the ECL technique

    Predicted band size : 67 kDa
    Observed band size : 67 kDa

References for Anti-ABCE1 antibody (ab117997)

ab117997 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab117997.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"