Overview

  • Product name
  • Description
    Rabbit polyclonal to ABCE1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 566-595 of Human ABCE1 (Accessions: NP_002931.2, NP_001035809.1).

  • Positive control
    • A549 cell line lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab123727 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 67 kDa.

Target

  • Function
    Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.
  • Sequence similarities
    Belongs to the ABC transporter superfamily. ABCE family.
    Contains 2 4Fe-4S ferredoxin-type domains.
    Contains 2 ABC transporter domains.
  • Cellular localization
    Cytoplasm. Mitochondrion. Localized to clusters of virus formation at the plasma membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2' 5' oligoadenylate binding protein antibody
    • 2''-5''-oligoadenylate-binding protein antibody
    • 2'5' oligoadenylate binding protein antibody
    • ABC 38 antibody
    • ABC38 antibody
    • ABCE 1 antibody
    • ABCE1 antibody
    • ABCE1_HUMAN antibody
    • ATP binding cassette sub family E (OABP) member 1 antibody
    • ATP binding cassette sub family E member 1 antibody
    • ATP-binding cassette sub-family E member 1 antibody
    • HuHP 68 antibody
    • HuHP68 antibody
    • OABP antibody
    • Ribonuclease 4 inhibitor antibody
    • Ribonuclease L (2' 5' oligoisoadenylate synthetase dependent) inhibitor antibody
    • Ribonuclease L (2'5' oligoisoadenylate synthetase dependent) inhibitor antibody
    • Ribonuclease L inhibitor antibody
    • RLI antibody
    • RNase L inhibitor antibody
    • RNASEL1 antibody
    • RNASELI antibody
    • RNS 4I antibody
    • RNS4I antibody
    see all

Images

  • Anti-ABCE1 antibody (ab123727) at 1/100 dilution + A549 cell line lysates at 35 µg

    Predicted band size : 67 kDa

References

ab123727 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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