Overview

  • Product name
  • Description
    Goat polyclonal to ABCE1
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chicken, Cow, Dog, Zebrafish, Cynomolgus monkey, Orangutan
  • Immunogen

    Synthetic peptide:

    KLNSIKDVEQKK

    from the C terminus of the protein human ABCE1 sequence according to NP_002931.1

  • Positive control
    • A431 cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab77367 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notes
    Peptide ELISA: Antibody detection limit dilution 1/8000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 67 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.
    • Sequence similarities
      Belongs to the ABC transporter superfamily. ABCE family.
      Contains 2 4Fe-4S ferredoxin-type domains.
      Contains 2 ABC transporter domains.
    • Cellular localization
      Cytoplasm. Mitochondrion. Localized to clusters of virus formation at the plasma membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • 2' 5' oligoadenylate binding protein antibody
      • 2''-5''-oligoadenylate-binding protein antibody
      • 2'5' oligoadenylate binding protein antibody
      • ABC 38 antibody
      • ABC38 antibody
      • ABCE 1 antibody
      • ABCE1 antibody
      • ABCE1_HUMAN antibody
      • ATP binding cassette sub family E (OABP) member 1 antibody
      • ATP binding cassette sub family E member 1 antibody
      • ATP-binding cassette sub-family E member 1 antibody
      • HuHP 68 antibody
      • HuHP68 antibody
      • OABP antibody
      • Ribonuclease 4 inhibitor antibody
      • Ribonuclease L (2' 5' oligoisoadenylate synthetase dependent) inhibitor antibody
      • Ribonuclease L (2'5' oligoisoadenylate synthetase dependent) inhibitor antibody
      • Ribonuclease L inhibitor antibody
      • RLI antibody
      • RNase L inhibitor antibody
      • RNASEL1 antibody
      • RNASELI antibody
      • RNS 4I antibody
      • RNS4I antibody
      see all

    Images

    References

    ab77367 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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