Overview

  • Product nameAnti-ABCF1 antibody
    See all ABCF1 primary antibodies
  • Description
    Rabbit polyclonal to ABCF1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rabbit, Horse, Guinea pig, Cow, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to a region between the C terminal amino acids 795-845 (VSHDARLITE TNCQLWVVEE QSVSQIDGDF EDYKREVLEA LGEVMVSRPR E) of Human ABCF1 (NP_001020262.1)

  • Positive control
    • Breast, colon or prostate carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab105045 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol. Likely to work on frozen sections.

Target

  • FunctionIsoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesBelongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
    Contains 2 ABC transporter domains.
  • Post-translational
    modifications
    Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2; inhibits association of EIF2 with ribosomes.
  • Cellular localizationCytoplasm. Nucleus, nucleoplasm. Nucleus envelope.
  • Information by UniProt
  • Database links
  • Alternative names
    • ABC27 antibody
    • ABC50 antibody
    • ABCF1 antibody
    • ABCF1_HUMAN antibody
    • ATP binding cassette 50 (TNF alpha stimulated) antibody
    • ATP binding cassette 50 antibody
    • ATP binding cassette sub family F member 1 antibody
    • ATP binding cassette, sub family F (GCN20), member 1 antibody
    • ATP-binding cassette 50 antibody
    • ATP-binding cassette sub-family F member 1 antibody
    • AU041969 antibody
    • D17Wsu166e antibody
    • EST123147 antibody
    • GCN20 antibody
    • TNF alpha stimulated ABC protein antibody
    • TNF-alpha-stimulated ABC protein antibody
    • TNFalpha inducible ATP binding protein antibody
    • wu:fb79c06 antibody
    • wu:fc39a05 antibody
    • wu:fj94a08 antibody
    • zgc:85667 antibody
    see all

Anti-ABCF1 antibody images

  • ab105045 at 1/250 dilution staining ABCF1 in formalin-fixed, paraffin-embedded Human colon carcinoma tissue.
    Detection: DAB staining

References for Anti-ABCF1 antibody (ab105045)

ab105045 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"