Overview

  • Product nameAnti-ABHD12 antibody
    See all ABHD12 primary antibodies
  • Description
    Rabbit polyclonal to ABHD12
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Guinea pig, Cow, Cat, Dog, Human, Pig
  • Immunogen

    Synthetic peptide: APSRSFRDFK VQFIPFHSDL GYRHKYIYKS PELPRILREF LGKSEPERQH, corresponding to a region within the C terminal amino acids 349-398 of Mouse ABHD12 (NP_077785).

  • Positive control
    • Mouse thymus lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferConstituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG

Applications

Our Abpromise guarantee covers the use of ab125325 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 45 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionHas 2-arachidonoylglycerol hydrolase activity (By similarity). May be a regulator of endocannabinoid signaling pathways.
  • Involvement in diseaseDefects in ABHD12 are the cause of polyneuropathy hearing loss ataxia retinitis pigmentosa and cataract (PHARC) [MIM:612674]. PHARC is a slowly progressive neurologic disorder with a variable phenotype resembling Refsum disease. Clinical features include sensorineural hearing loss, visual problems related to cataracts, retinitis pigmentosa, pes cavus, ataxic and/or spastic gait disturbances with a progressive sensorimotor peripheral neuropathy. Other features include hyporeflexia, hyperreflexia, extensor plantar responses.
  • Sequence similaritiesBelongs to the serine esterase family.
  • Post-translational
    modifications
    Glycosylated.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2-arachidonoylglycerol hydrolase antibody
    • 6330583M11Rik antibody
    • ABD12_HUMAN antibody
    • ABHD12 antibody
    • ABHD12A antibody
    • Abhydrolase domain containing protein 12 antibody
    • Abhydrolase domain-containing protein 12 antibody
    • AI431047 antibody
    • AW547313 antibody
    • BEM46L2 antibody
    • C20orf22 antibody
    • Monoacylglycerol lipase ABHD12 antibody
    • RP23-241M12.2 antibody
    see all

Anti-ABHD12 antibody images

  • Anti-ABHD12 antibody (ab125325) at 1 µg/ml + Mouse thymus lysate at 10 µg

    Predicted band size : 45 kDa

References for Anti-ABHD12 antibody (ab125325)

ab125325 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"