Overview

  • Product name
  • Description
    Rabbit polyclonal to ABIN3
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    A KLH conjugated synthetic peptide corresponding to the C terminal of Human ABIN3

  • Positive control
    • IHC-P: Human adrenal tissue WB: Human spleen tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab113748 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 38 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Relevance
    ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
  • Cellular localization
    Cytoplasmic and Nuclear (based on other ABIN family members).
  • Database links
  • Alternative names
    • A20 binding inhibitor of NF kappa B activation 3 antibody
    • ABIN 3 antibody
    • ABIN 3 beta antibody
    • FLJ21162 antibody
    • LIND antibody
    • Listeria induced antibody
    • Listeria induced gene protein antibody
    • TNFAIP3 interacting protein 3 antibody
    • TNFAIP3 interacting protein 3 beta antibody
    • TNIP3 antibody
    • TNIP3 beta antibody
    see all

Images

  • All lanes : Anti-ABIN3 antibody (ab113748) at 1 µg/ml

    Lane 1 : Human spleen tissue lysate
    Lane 2 : Human spleen tissue lysate with blocking peptide


    Predicted band size : 38 kDa
  • ab113748, at 5 µg/ml, staining ABIN3 in formalin fixed, paraffin embedded, Human adrenal tissue by Immunohistochemistry

References

ab113748 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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