• Product nameAnti-ACADSB antibody
    See all ACADSB primary antibodies
  • Description
    Rabbit polyclonal to ACADSB
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Saccharomyces cerevisiae, Drosophila melanogaster
  • Immunogen

    Synthetic peptide: GLRASSTCPL TFENVKVPEA NILGQIGHGY KYAIGSLNEG RIGIAAQMLG , corresponding to internal sequence amino acids 254-303 of Human ACADSB (NP_001600).

  • Positive control
    • Fetal liver lysate


Our Abpromise guarantee covers the use of ab81644 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 47 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1:1562500.


  • FunctionHas greatest activity toward short branched chain acyl-CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl-CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent.
  • Tissue specificityUbiquitous.
  • PathwayLipid metabolism; mitochondrial fatty acid beta-oxidation.
  • Involvement in diseaseDefects in ACADSB are the cause of short/branched-chain acyl-CoA dehydrogenase deficiency (SBCADD) [MIM:610006]; also known as 2-methylbutyryl-CoA dehydrogenase deficiency or 2-methylbutyryl glycinuria. SBCADD is an autosomal recessive disorder and consists of a defect in catabolism of L-isoleucine which is characterized by an increase of 2-methylbutyrylglycine and 2-methylbutyrylcarnitine in blood and urine. Affected individuals have seizures and psychomotor delay as the main clinical features.
  • Sequence similaritiesBelongs to the acyl-CoA dehydrogenase family.
  • Cellular localizationMitochondrion matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2 MEBCAD antibody
    • 2 methyl branched chain acyl CoA dehydrogenase antibody
    • 2 methylbutyryl CoA dehydrogenase antibody
    • 2 methylbutyryl coenzyme A dehydrogenase antibody
    • 2-MEBCAD antibody
    • 2-methyl branched chain acyl-CoA dehydrogenase antibody
    • 2-methylbutyryl-CoA dehydrogenase antibody
    • 2-methylbutyryl-coenzyme A dehydrogenase antibody
    • ACAD7 antibody
    • ACADSB antibody
    • ACDSB_HUMAN antibody
    • acyl CoA dehydrogenase, short/branched chain antibody
    • acyl Coenzyme A dehydrogenase short branched chain antibody
    • mitochondrial antibody
    • OTTHUMP00000020685 antibody
    • OTTHUMP00000046795 antibody
    • SBCAD antibody
    • Short/branched chain specific acyl-CoA dehydrogenase antibody
    • short/branched chain specific acyl-CoA dehydrogenase, mitochondrial antibody
    see all

Anti-ACADSB antibody images

  • Anti-ACADSB antibody (ab81644) at 1 µg/ml + Fetal liver lysate at 10 µg with skim milk/ PBS buffer at 5 %

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 47 kDa
    Observed band size : 39 kDa (why is the actual band size different from the predicted?)

References for Anti-ACADSB antibody (ab81644)

ab81644 has not yet been referenced specifically in any publications.

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