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AbcamBiochemicals (Asc-251)

ACEA (Arachidonyl-2-chloroethylamide) (ab120251)

Q&A (2)

Overview

  • Product nameACEA (Arachidonyl-2-chloroethylamide)
  • Description
    Potent, selective CB1 agonist
  • Alternative names
    Arachidonyl-2-chloroethylamide
  • Biological descriptionPotent and selective neuronal CB1 cannabinoid receptor agonist ( Ki = 1.4 nM). Displays > 1400-fold selectivity over CB2 receptors. Active in vivo.
  • Purity> 98%

    • Properties

  • Chemical name(5Z,8Z,11Z,14Z)-N-(2-Chloroethyl)icosa-5,8,11,14-tetraenamide
  • Molecular Weight365.98
  • Chemical structureChemical Structure
  • Molecular formulaC22H36ClNO
  • CAS Number220556-69-4
  • PubChem identifier5311006
  • Storage instructionsStore at -20°C (desiccating conditions).
  • Solubility overviewSoluble in DMSO to 100 mM and in ethanol to 100 mM
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  • SMILESClCCNC(=O)CCC/C=CC/C=CC/C=CC/C=CCCCCC
  • Source

    Synthetic

  • Research Areas

    • References for ACEA (Arachidonyl-2-chloroethylamide) (ab120251)

    This product has been referenced in:
    • Price TJ  et al. Modulation of trigeminal sensory neuron activity by the dual cannabinoid-vanilloid agonists anandamide, N-arachidonoyl-dopamine and arachidonyl-2-chloroethylamide. Br J Pharmacol 141:1118-30 (2004). Read more (PubMed: 15006899) »
    • Baker CL & McDougall JJ The cannabinomimetic arachidonyl-2-chloroethylamide (ACEA) acts on capsaicin-sensitive TRPV1 receptors but not cannabinoid receptors in rat joints. Br J Pharmacol 142:1361-7 (2004). Read more (PubMed: 15277316) »
    • Hillard CJ  et al. Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1). J Pharmacol Exp Ther 289:1427-33 (1999). Read more (PubMed: 10336536) »

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    Phone call requesting information relating to the volume of ACEA (Arachidonyl-2-chloroethylamide) (ab120251) and any side products that may be present.

    Thank you for contacting us yesterday and sorry for the delay in getting back to you.

    I now have further information to share with you in regards to the ACEA (Arachidonyl-2-chloroethylamide), ab120251.

    As discussed over the phone, the co...

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    In which solvent ab120251 is dissolved?

    Thank you for contacting us.

    This compound (http://www.abcam.com/ACEA-Arachidonyl-2-chloroethylamide-ab120251.html) is the pure version, which is supplied as a colourless liquid, this has an oily appearance. If you want to further dissolve it int...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"