Anti-Acetyl Coenzyme A Carboxylase (phospho S80) antibody (ab53688)

Overview

  • Product nameAnti-Acetyl Coenzyme A Carboxylase (phospho S80) antibody
    See all Acetyl Coenzyme A Carboxylase primary antibodies
  • Description
    Rabbit polyclonal to Acetyl Coenzyme A Carboxylase (phospho S80)
  • SpecificityThe antibody detects endogenous levels of Human Acetyl Coenzyme A Carboxylase only when phosphorylated at serine 80 (Serine 79 in Mouse and Rat).
  • Tested applicationsSuitable for: IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic phosphopeptide derived from human Acetyl Coenzyme A Carboxylase around the phosphorylation site of serine 80 (S-M-SP-G-L).

  • Positive control
    • Human skeletal muscle tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab53688 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
ELISA 1/5000.

Target

  • FunctionCatalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
  • Tissue specificityExpressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver.
  • PathwayLipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.
  • Involvement in diseaseAcetyl-CoA carboxylase 1 deficiency
  • Sequence similaritiesContains 1 ATP-grasp domain.
    Contains 1 biotin carboxylation domain.
    Contains 1 biotinyl-binding domain.
    Contains 1 carboxyltransferase domain.
  • Post-translational
    modifications
    Phosphorylation on Ser-1263 is required for interaction with BRCA1.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • ACAC antibody
    • ACACA antibody
    • ACACA_HUMAN antibody
    • ACACB antibody
    • ACC alpha antibody
    • ACC antibody
    • ACC beta antibody
    • ACC-alpha antibody
    • ACC1 antibody
    • ACC2 antibody
    • ACCA antibody
    • ACCB antibody
    • Acetyl CoA carboxylase 1 antibody
    • Acetyl CoA carboxylase 2 antibody
    • Acetyl CoA carboxylase alpha antibody
    • Acetyl CoA carboxylase beta antibody
    • Acetyl Coenzyme A carboxylase alpha antibody
    • Acetyl Coenzyme A carboxylase beta antibody
    • Biotin carboxylase antibody
    • COA1 antibody
    • COA2 antibody
    • HACC275 antibody
    • OTTHUMP00000164069 antibody
    • OTTHUMP00000164070 antibody
    • OTTHUMP00000164076 antibody
    • OTTHUMP00000240532 antibody
    see all

Anti-Acetyl Coenzyme A Carboxylase (phospho S80) antibody images

  • ab53688 at 1/50 dilution staining Acetyl Coenzyme A Carboxylase in human skeletal muscle by Immunohistochemistry, Paraffin embedded tissue, in the absence or presence of the immunising peptide.

References for Anti-Acetyl Coenzyme A Carboxylase (phospho S80) antibody (ab53688)

ab53688 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"