Anti-acetyl Lysine antibody [7F8] (Phycoerythrin) (ab92766)


  • Product nameAnti-acetyl Lysine antibody [7F8] (Phycoerythrin)
    See all acetyl Lysine primary antibodies
  • Description
    Mouse monoclonal [7F8] to acetyl Lysine (Phycoerythrin)
  • ConjugationPhycoerythrin. Ex: 488nm, Em: 575nm
  • Specificityab92766 is a pan-specific acetyl lysine antibody.
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Cow, Human, Bird
  • Immunogen

    Acetylated KLH(keyhole limpet hemocyanin)


  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C. Store In the Dark.
  • Storage bufferPreservative: 2mM Sodium Azide
    Constituents: 100mM Sodium chloride, 100mM Sodium phosphate, pH 7.2
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityMonoclonal
  • Clone number7F8
  • IsotypeIgG1
  • Research areas


Our Abpromise guarantee covers the use of ab92766 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notesFlow Cyt: Use at a concentration of 3 µg/ml.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceIn the nucleus, DNA is tightly packed into nucleosomes generating an environment which is highly repressive towards DNA processes such as transcription. Acetylation of lysine residues within proteins has emerged as an important mechanism used by cells to overcome this repression. The acetylation of non-histone proteins such as transcription factors, as well as histones appears to be involved in this process. Acetylation may result in structural transitions as well as specific signaling within discrete chromatin domains. The role of acetylation in intracellular signaling has been inferred from the binding of acetylated peptides by the conserved bromodomain. Furthermore, recent findings suggest that bromodomain/acetylated-lysine recognition can serve as a regulatory mechanism in protein-protein interactions in numerous cellular processes such as chromatin remodeling and transcriptional activation. The reversible lysine acetylation of histones and non-histone proteins plays a vital role in the regulation of many cellular processes including chromatin dynamics and transcription, gene silencing, cell cycle progression, apoptosis, differentiation, DNA replication, DNA repair, nuclear import, and neuronal repression. More than 20 acetyltransferases and 18 deacetylases have been identified so far, but the mechanistic details of substrate selection and site specificity of these enzymes remain unclear. Over 40 transcription factors and 30 other nuclear, cytoplasmic, bacterial, and viral proteins have been shown to be acetylated in vivo.
    • Alternative names
      • pan acetyl Lysine antibody

    References for Anti-acetyl Lysine antibody [7F8] (Phycoerythrin) (ab92766)

    ab92766 has not yet been referenced specifically in any publications.

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