Anti-Acetylcholinesterase antibody (HRP) (ab7397)

Overview

  • Product nameAnti-Acetylcholinesterase antibody (HRP)
    See all Acetylcholinesterase primary antibodies
  • Description
    Goat polyclonal to Acetylcholinesterase (HRP)
  • ConjugationHRP
  • Tested applicationsSuitable for: Electron Microscopy, ELISA, IHC-Fr, WBmore details
  • Species reactivity
    Reacts with: Cow
  • Immunogen

    Full length native protein (purified) corresponding to Cow Acetylcholinesterase. Purified from Bovine Erythrocytes
    Database link: P23795

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferpH: 7.60
    Preservative: 0.01% Gentamicin sulphate
    Constituents: 0.88% Sodium chloride, 1% BSA, 0.42% Potassium phosphate
  • Concentration information loading...
  • PurityIgG fraction
  • Purification notesThis product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab7397 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Electron Microscopy Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
WB Use at an assay dependent concentration.

Target

  • FunctionTerminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.
  • Tissue specificityIsoform H is highly expressed in erythrocytes.
  • Sequence similaritiesBelongs to the type-B carboxylesterase/lipase family.
  • Cellular localizationCell membrane; Cell junction > synapse. Secreted. Cell membrane and Nucleus. Only observed in apoptotic nuclei.
  • Information by UniProt
  • Database links
  • Alternative names
    • ACEE antibody
    • ACES_HUMAN antibody
    • Acetylcholinesterase antibody
    • AChE antibody
    • Apoptosis related acetylcholinesterase antibody
    • ARACHE antibody
    • N ACHE antibody
    • N-ACHE antibody
    • YT antibody
    • YT blood group antibody
    see all

References for Anti-Acetylcholinesterase antibody (HRP) (ab7397)

ab7397 has not yet been referenced specifically in any publications.

Product Wall

This antibody has been tested in IHC on frozen sections, not on paraffin embedded sections - I shall add this information to be datasheet. As for the cross reactivity with Human tissue, it is also unknown, but quite likely due to the nature of the poly...

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Sorry, we don't have any references for or images of this antibody being used in IHC of brain sections. This antibody was raised against the bovine antigen; although cross-reactivity with acetylcholine esterase from other species is expected it has not...

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Although this antibody was raised against AChE from bovine erythrocytes, we expect it to recognise rat brain AChE although its cross-reactivity with the rat antigen has not been specifically tested. Therefore, I recommend that you try this antibody und...

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We haven't tested this antibody in immunohistochemistry, just ELISA and Western.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"