Overview

  • Product nameAnti-Acinus antibody [2005C3a]See all Acinus primary antibodies ...
  • Description
    Mouse monoclonal [2005C3a] to Acinus
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant human Acinus fragment carrying 50-200 aa

  • Positive control
    • recombinant immunozing fragment

Properties

Applications

Our Abpromise guarantee covers the use of ab50827 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Detects a band of approximately 200 kDa (predicted molecular weight: 152 kDa).

Target

  • FunctionComponent of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesContains 1 SAP domain.
  • Post-translational
    modifications
    Undergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • ACIN 1 antibody
    • ACIN1 antibody
    • ACINU_HUMAN antibody
    • ACINUS antibody
    • ACN antibody
    • Apoptotic chromatin condensation inducer 1 antibody
    • Apoptotic chromatin condensation inducer in the nucleus antibody
    • DKFZp667N107 antibody
    • fSAP152 antibody
    • functional spliceosome-associated protein 152 antibody
    • KIAA0670 antibody
    see all

Anti-Acinus antibody [2005C3a] images

  • Anti-Acinus antibody [2005C3a] (ab50827) at 1/50 dilution + A2058 whole cell lysate at 50 µg

    Secondary
    anti-mouse IgG at 1/2500 dilution

    Predicted band size : 152 kDa

References for Anti-Acinus antibody [2005C3a] (ab50827)

This product has been referenced in:
  • Huang Y  et al. Global tumor protein p53/p63 interactome: Making a case for cisplatin chemoresistance. Cell Cycle 11:2367-79 (2012). WB ; Human . Read more (PubMed: 22672905) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"