Anti-Aconitase 1 (phospho S711) antibody (ab62451)

Overview

  • Product nameAnti-Aconitase 1 (phospho S711) antibody
    See all Aconitase 1 primary antibodies
  • Description
    Rabbit polyclonal to Aconitase 1 (phospho S711)
  • Specificityab62451 detects endogenous levels of Aconitase 1 only when phosphorylated at serine 711.
  • Tested applicationsSuitable for: IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic phosphopeptide derived from human Aconitase 1 around the phosphorylation site of serine 711 (Y-G-SP-R-R).

  • Positive control
    • Human thyroid gland tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab62451 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
ELISA 1/10000.

Target

  • FunctionIron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.
    Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
  • Sequence similaritiesBelongs to the aconitase/IPM isomerase family.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • ACO 1 antibody
    • ACO1 antibody
    • ACOC_HUMAN antibody
    • Aconitase 1 soluble antibody
    • Aconitase antibody
    • Aconitase1 antibody
    • Aconitate hydratase antibody
    • ACONS antibody
    • Citrate hydro lyase antibody
    • Citrate hydro-lyase antibody
    • Cytoplasmic aconitate hydratase antibody
    • Ferritin repressor protein antibody
    • IRE BP 1 antibody
    • IRE-BP 1 antibody
    • IREB 1 antibody
    • IREB1 antibody
    • IREBP antibody
    • IREBP1 antibody
    • Iron regulatory protein 1 antibody
    • Iron responsive element binding protein 1 antibody
    • Iron-responsive element-binding protein 1 antibody
    • IRP 1 antibody
    • IRP1 antibody
    • OTTHUMP00000045233 antibody
    see all

Anti-Aconitase 1 (phospho S711) antibody images

  • ab62451, at 1/50 dilution, staining Aconitase 1 in paraffin embedded human thyroid gland tissue by Immunohistochemistry in the absence or presence of the immunising peptide.

References for Anti-Aconitase 1 (phospho S711) antibody (ab62451)

ab62451 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"