Overview

  • Product name
    Anti-ACOX1 antibody - C-terminal
    See all ACOX1 primary antibodies
  • Description
    Rabbit polyclonal to ACOX1 - C-terminal
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A KLH conjugated synthetic peptide selected from the C-terminal region of human ACOX1.

Properties

Applications

Our Abpromise guarantee covers the use of ab71483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50 - 1/100. Detects a band of approximately 74 kDa (predicted molecular weight: 74 kDa).
ELISA 1/1000.

Target

  • Function
    Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA.
  • Tissue specificity
    Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart.
  • Pathway
    Lipid metabolism; peroxisomal fatty acid beta-oxidation.
  • Involvement in disease
    Adrenoleukodystrophy, pseudoneonatal
  • Sequence similarities
    Belongs to the acyl-CoA oxidase family.
  • Cellular localization
    Peroxisome.
  • Information by UniProt
  • Database links
  • Alternative names
    • ACOX antibody
    • ACOX1 antibody
    • ACOX1_HUMAN antibody
    • Acyl CoA oxidase 1 palmitoyl antibody
    • Acyl CoA oxidase straight chain antibody
    • AOX antibody
    • EC 1.3.3.6 antibody
    • PALMCOX antibody
    • Palmitoyl CoA oxidase antibody
    • Palmitoyl-CoA oxidase antibody
    • Peroxisomal acyl coenzyme A oxidase 1 antibody
    • Peroxisomal acyl-coenzyme A oxidase 1 antibody
    • Peroxisomal fatty acyl CoA oxidase antibody
    • SCOX antibody
    • Straight chain acyl CoA oxidase antibody
    • Straight-chain acyl-CoA oxidase antibody
    see all

Images

  • All lanes : Anti-ACOX1 antibody - C-terminal (ab71483) at 1/50 dilution

    Lane 1 : Non-transfected 293 cell lysates
    Lane 2 : ACOX1 (clone RB04652) transfected 293 cell lysates

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 74 kDa
    Observed band size : 74 kDa

References

ab71483 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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