Overview

  • Product name
    Anti-ACPL2 antibody
  • Description
    Rabbit polyclonal to ACPL2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 306-335 of Human ACPL2 (Accessions: NP_689495.1, NP_001032249.1, Q8TE99)

  • Positive control
    • HL-60 cell line lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab124190 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 55 kDa.

Target

  • Function
    Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains.
  • Tissue specificity
    Widely expressed. Strongly expressed in spleen, fetal liver, moderately in placenta, pancreas, kidney, thymus and colon.
  • Sequence similarities
    Belongs to the histidine acid phosphatase family.
  • Cellular localization
    Golgi apparatus membrane. Colocalizes to Golgi apparatus in a B3GAT3-dependent manner.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2-phosphoxylose phosphatase 1 antibody
    • acid phosphatase-like 2 antibody
    • Acid phosphatase-like protein 2 antibody
    • EC=3.1.3.2 antibody
    • epididymis luminal protein 124 antibody
    • PXYLP1 antibody
    • PXYP1_HUMAN antibody
    • Xylosyl phosphatase antibody
    see all

Images

  • Anti-ACPL2 antibody (ab124190) at 1/100 dilution + HL60 cell line lysates at 35 µg

    Predicted band size : 55 kDa

References

ab124190 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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