Overview

  • Product name
    Anti-ACSL1 antibody [EPR13499]
    See all ACSL1 primary antibodies
  • Description
    Rabbit monoclonal [EPR13499] to ACSL1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
    Unsuitable for: Flow Cyt,ICC/IF or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human ACSL1 aa 650 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
    Database link: P33121

  • Positive control
    • HepG2 and Human fetal liver lysates; Human kdney and liver tissues.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Associated products

Applications

Our Abpromise guarantee covers the use of ab177958 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/250.
WB 1/1000 - 1/10000. Predicted molecular weight: 78 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF or IP.
  • Target

    • Function
      Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate.
    • Tissue specificity
      Highly expressed in liver, heart, skeletal muscle, kidney and erythroid cells, and to a lesser extent in brain, lung, placenta and pancreas.
    • Sequence similarities
      Belongs to the ATP-dependent AMP-binding enzyme family.
    • Developmental stage
      Expressed during the early stages of erythroid development while expression is very low in reticulocytes and young erythrocytes.
    • Cellular localization
      Mitochondrion outer membrane. Peroxisome membrane. Microsome membrane. Endoplasmic reticulum membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • ACS 1 antibody
      • ACS1 antibody
      • ACSL 1 antibody
      • ACSL1 antibody
      • ACSL1_HUMAN antibody
      • Acyl CoA synthetase 1 antibody
      • Acyl CoA synthetase long chain family member 1 antibody
      • Acyl-CoA synthetase 1 antibody
      • FACL 1 antibody
      • FACL 2 antibody
      • FACL1 antibody
      • FACL2 antibody
      • Fatty acid Coenzyme A ligase long chain 1 antibody
      • Fatty acid Coenzyme A ligase long chain 2 antibody
      • LACS 1 antibody
      • LACS 2 antibody
      • LACS antibody
      • LACS1 antibody
      • LACS2 antibody
      • Lignoceroyl CoA synthase antibody
      • Long chain acyl CoA synthetase 1 antibody
      • Long chain acyl CoA synthetase 2 antibody
      • Long chain fatty acid CoA ligase 1 antibody
      • Long chain fatty acid CoA ligase 2 antibody
      • Long chain fatty acid coenzyme A ligase 1 antibody
      • Long-chain acyl-CoA synthetase 1 antibody
      • Long-chain acyl-CoA synthetase 2 antibody
      • Long-chain fatty acid-CoA ligase 2 antibody
      • Long-chain-fatty-acid--CoA ligase 1 antibody
      • Palmitoyl CoA ligase 1 antibody
      • Palmitoyl CoA ligase 2 antibody
      • Palmitoyl-CoA ligase 1 antibody
      • Palmitoyl-CoA ligase 2 antibody
      • Paltimoyl CoA ligase 1 antibody
      see all

    Images

    • Immunohistochemical analysis of Human liver tissue labeling ACSL1 using ab177958 at 1/100 dilution.

    • Immunohistochemical analysis of Human kidney tissue labeling ACSL1 using ab177958 at 1/100 dilution.

    • All lanes : Anti-ACSL1 antibody [EPR13499] (ab177958) at 1/1000 dilution

      Lane 1 : HepG2 cell lysate
      Lane 2 : Human fetal liver lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 78 kDa

    References

    This product has been referenced in:
    • Yang L  et al. High expression of long chain acyl-coenzyme A synthetase 1 in peripheral blood may be a molecular marker for assessing the risk of acute myocardial infarction. Exp Ther Med 14:4065-4072 (2017). Read more (PubMed: 29104625) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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