Overview

  • Product name
  • Description
    Rabbit polyclonal to ACSL6
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 452-687 of Human ACSL6.

  • Positive control
    • Jurkat, Raji, K562, THP-1, NCI-H929, mouse heart and rat heart lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab154094 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 78 kDa.

Target

  • Relevance
    ACSL6 belongs to the ATP-dependent AMP-binding enzyme family. It is involved in the activation of long-chain fatty acids for both synthesis of cellular lipids and degradation via beta-oxidation. ACSL6 plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. ACSL6 is expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derived from fetal liver, haemopoietic stem cells from cord blood, bone marrow, and brain. There are three named isoforms.
  • Cellular localization
    Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein.
  • Database links
  • Alternative names
    • ACS2 antibody
    • Acyl CoA synthetase long chain family member 6 antibody
    • FACL6 antibody
    • Fatty acid Coenzyme A ligase, long chain 6 antibody
    • LACS 6 antibody
    • LACS2 antibody
    • LACS5 antibody
    • Long chain acyl CoA synthetase 6 antibody
    • Long chain fatty acid CoA ligase 6 antibody
    • Long fatty acyl CoA synthetase 2 antibody
    see all

Images

  • All lanes : Anti-ACSL6 antibody (ab154094) at 1/1000 dilution

    Lane 1 : Jurkat whole cell
    lysate
    Lane 2 : Raji whole cell
    lysate
    Lane 3 : K562 whole cell
    lysate
    Lane 4 : THP-1 whole cell
    lysate
    Lane 5 : NC I-H929 whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 78 kDa



    7.5% SDS-PAGE
  • Anti-ACSL6 antibody (ab154094) at 1/1000 dilution + Mouse heart
    lysate at 50 µg

    Predicted band size: 78 kDa



    7.5% SDS-PAGE
  • Anti-ACSL6 antibody (ab154094) at 1/10000 dilution + Rat heart lysate at 50 µg

    Predicted band size: 78 kDa



    7.5% SDS-PAGE

References

ab154094 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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