Overview

  • Product name
  • Description
    Rabbit polyclonal to ACTBL2
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A 16 amino acid peptide from intermediate residues of Human ACTBL2 protein.

  • Positive control
    • WB: Human fetal liver or thymus lysate; IHC-P: Human fetal kidney tissue.

Properties

  • Form
    Lyophilised:add 200ul distilled water
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, PBS, pH 7.2
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab100869 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 42 kDa.
IHC-P 1/100 - 1/500.

Target

  • Function
    Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
  • Sequence similarities
    Belongs to the actin family.
  • Post-translational
    modifications
    Oxidation of Met-45 and Met-48 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promote actin repolymerization.
    Monomethylation at Lys-85 (K84me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration.
  • Cellular localization
    Cytoplasm, cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • ACT antibody
    • ACTBL_HUMAN antibody
    • ACTBL2 antibody
    • actin like protein antibody
    • actin, beta like 2 antibody
    • Beta-actin-like protein 2 antibody
    • DKFZp686D0972 antibody
    • kappa actin antibody
    • Kappa-actin antibody
    see all

Images

  • All lanes : Anti-ACTBL2 antibody (ab100869) at 1/500 dilution

    Lane 1 : Human fetal liver lysate
    Lane 2 : Human fetal thymus lysate


    Predicted band size : 42 kDa
  • Formalin-fixed, paraffin-embedded Human fetal kidney tissue labelled with ab100869 at 1/100 dilution. Note: cytoplasmic staining.

References

ab100869 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab100869.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up