Anti-activated Notch1 antibody (ab8925)

ab8925 has been referenced in 23 publications.

1. Chen L et al. The Role of Notch 1 Activation in Cardiosphere Derived Cell Differentiation. Stem Cells Dev : (2012). PubMed: 22239539
2. Zhou D et al. Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance. Proc Natl Acad Sci U S A 108:E1312-20 (2011). PubMed: 22042863
3. Hao L et al. Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells. Oncogene 29:201-13 (2010). WB; Human. PubMed: 19838210
4. Radke AL et al. Mature human eosinophils express functional Notch ligands mediating eosinophil autocrine regulation. Blood 113:3092-101 (2009). Electron Microscopy, Flow Cyt; Human. PubMed: 19171875
5. Rodilla V et al. Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer. Proc Natl Acad Sci U S A 106:6315-20 (2009). ChIP; Human. PubMed: 19325125
6. Sivasankaran B et al. Tenascin-C is a novel RBPJkappa-induced target gene for Notch signaling in gliomas. Cancer Res 69:458-65 (2009). IHC-P; Human. PubMed: 19147558
7. Liu Z et al. Epithelial transformation by KLF4 requires Notch1 but not canonical Notch1 signaling. Cancer Biol Ther 8:1840-51 (2009). WB, IHC-P; Human. PubMed: 19717984
8. Rasul S et al. Inhibition of gamma-secretase induces G2/M arrest and triggers apoptosis in breast cancer cells. Br J Cancer 100:1879-88 (2009). WB; Human. PubMed: 19513078
9. Song LL et al. Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells. Oncogene 27:5833-44 (2008). WB; Human. PubMed: 18560356
10. Ma QH et al. A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis. Nat Cell Biol 10:283-94 (2008). WB; Mouse. PubMed: 18278038
11. Brack AS et al. A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis. Cell Stem Cell 2:50-9 (2008). ICC/IF, IHC-Fr; Mouse. PubMed: 18371421
12. Grigorian A et al. Alterations in the Notch4 pathway in cerebral endothelial cells by the HIV aspartyl protease inhibitor, nelfinavir. BMC Neurosci 9:27 (2008). ICC/IF; Human. PubMed: 18302767
13. Keilani S & Sugaya K Reelin induces a radial glial phenotype in human neural progenitor cells by activation of Notch-1. BMC Dev Biol 8:69 (2008). WB; Human. PubMed: 18593473
14. Carlson ME et al. Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells. Nature 454:528-32 (2008). WB; Mouse. PubMed: 18552838
15. Djalilian AR et al. Down-regulation of Notch signaling during corneal epithelial proliferation. Mol Vis 14:1041-9 (2008). PubMed: 18552977
16. Efstratiadis A et al. Notch, Myc and breast cancer. Cell Cycle 6:418-29 (2007). PubMed: 17329972
17. Niimi H et al. Notch signaling is necessary for epithelial growth arrest by TGF-beta. J Cell Biol 176:695-707 (2007). PubMed: 17325209
18. Garg P et al. Matrix metalloproteinase-9 regulates MUC-2 expression through its effect on goblet cell differentiation. Gastroenterology 132:1877-89 (2007). PubMed: 17484881
19. Vauclair S et al. Corneal epithelial cell fate is maintained during repair by Notch1 signaling via the regulation of vitamin A metabolism. Dev Cell 13:242-53 (2007). IP. PubMed: 17681135
20. Estrach S et al. Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis. Development 133:4427-38 (2006). PubMed: 17035290
21. Liu ZJ et al. Inhibition of endothelial cell proliferation by Notch1 signaling is mediated by repressing MAPK and PI3K/Akt pathways and requires MAML1. FASEB J 20:1009-11 (2006). WB; Human. PubMed: 16571776
22. Conboy IM et al. Rejuvenation of aged progenitor cells by exposure to a young systemic environment. Nature 433:760-4 (2005). PubMed: 15716955
23. Balint K et al. Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression. J Clin Invest 115:3166-76 (2005). WB; Human. PubMed: 16239965