Active Clostridium botulinum Exoenzyme C3 full length protein (ab63835)

Overview

  • Product nameActive Clostridium botulinum Exoenzyme C3 full length protein
  • Description
    Clostridium botulinum Exoenzyme C3 full length protein

Description

  • NatureNatural
  • SourceNative
  • Amino Acid Sequence

Specifications

Our Abpromise guarantee covers the use of ab63835 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 90 % by SDS-PAGE.
    ab63835 was highly purified from the supernatant of the culture of Clostridium botulinum type C by cation exchange, hydroxyapatite and gel filtration columns. No toxic effect was observed in two mice injected with 5 ug of C3 enzyme, showing little contamination of lethal toxins in this preparation.
  • FormLiquid
  • Additional Notes

    This protein is derived from a pathogenic organism, and may be involved in a disease process, consequently exposure may have adverse health effects.

     

    ab63835 can be used for studies on the Rho-dependent signaling pathways in animal cells in vivo and in vitro and for the study of ADP-ribosylation of small GTP proteins, such as Rho and Rac proteins.

    Its activity tested as tested and stimulation of human keratinocytes in culture was observed at 50 ng/ml.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50% Glycerol, 5mM Sodium phosphate buffer, pH 6.0

General info

  • RelevanceMono-ADP-ribosyltransferase C3 from Clostridium botulinum D phage (Clostridium botulinum D bacteriophage). ADP-ribosylates eukaryotic Rho and Rac proteins on an asparagine residue. It has a Mass of 27.8kDa.

Active Clostridium botulinum Exoenzyme C3 full length protein images

  • ab63835 on SDS-PAGE (CBB staining). Molecular Weight: ~27.8 kDa.

References for Active Clostridium botulinum Exoenzyme C3 full length protein (ab63835)

ab63835 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"