Active cow IL13 full length protein (ab87383)

Overview

Description

  • NatureRecombinant
  • SourceYeast
  • Amino Acid Sequence
    • SpeciesCow
    • SequenceSPVPSATALK ELIEELVNIT QNQKVPLCNG SMVWSLNLTS SMYCAALDSL ISISNCSVIQ RTKRMLNALC PHKPSAKQVS SEYVRDTKIE VAQFLKDLLR HSRIVFRNER FN
    • Amino acids0 to 0

Specifications

Our Abpromise guarantee covers the use of ab87383 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityThe biological activity of recombinant bovine IL13 was measured in a cell proliferation assay using the human TF1 cell line. The ED50 for this effect is typically 20 - 30 ng/mL.
  • Applications

    Cellular activation

    SDS-PAGE

  • Purity> 95 % by SDS-PAGE.
    ab87383 is purified by Ion-exchange chromatography.
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Store at -20°C. Stable for 12 months at -20°C

    Preservative: None
    Constituents: 10% Trehalose, 1.0X PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • ReconstitutionReconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.

General info

  • Alternative names
    • Allergic rhinitis
    • ALRH
    • BHR1
    • Bronchial hyperresponsiveness 1 (bronchial asthma)
    • IL 13
    • IL-13
    • Il13
    • IL13_HUMAN
    • Interleukin 13
    • Interleukin-13
    • MGC116786
    • MGC116788
    • MGC116789
    • NC30
    • P600
    see all
  • FunctionCytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.
  • Involvement in diseaseDefects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:607154]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.
  • Sequence similaritiesBelongs to the IL-4/IL-13 family.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Active cow IL13 full length protein (ab87383)

ab87383 has not yet been referenced specifically in any publications.

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