Active HIV1 gp120 protein fragment (ab73769)

Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • Amino acids30 to 110

Specifications

Our Abpromise guarantee covers the use of ab73769 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityab73769 is immunoreactive with all sera of HIV1 infected individuals.
  • Applications

    Western blot

    ELISA

  • Purity> 95 % by SDS-PAGE.
    Purity is greater than 95.0% as determined by RP-HPLC and SDS-PAGE.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 8M Urea, 100mM Sodium phosphate, 10mM Tris HCl, pH 4.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General info

  • Alternative names
    • Glycoprotein 120
    • gp120
    • SU
    • Surface protein
  • RelevanceHIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
  • Cellular localizationEnvelope surface glycoprotein.

References for Active HIV1 gp120 protein fragment (ab73769)

ab73769 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. The link does bring you to the sequence for the full protein and from there you can pull out the actual sequence of the protein fragment which is aa 3-110 as stated on the datasheet. I am not sure why it comes up highlighte...

Read More

DISCOUNT CODE: *
Expiration date: *

I am very pleased to hear you would like to accept our offer and test ab73769 in ELISPOT. This code will give you: 1 free PROTEIN before the expiration date. To redeem this offer, please submit an Abrevi...

Read More

Thank you for contacting Abcam about ab73769. The protein sequence that you requested can be obtained by clicking on the link below. It can also be found by using the uniprot ID#P04578. http://www.uniprot.org/blast/?about=P04578[33-511] ...

Read More

Thank you for your phone call. DISCOUNT CODE: xxx for ab73769 DISCOUNT CODE: xxx for ab69717 Expiration date: xxx I am very pleased to hear you would like to accept our offer and test ab73769 and ab69717 in Functional Studies...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"