Active human beta Defensin 1 full length protein (ab50048)

Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceDHYNCVSSGG QCLYSACPIF TKIQGTCYRG KAKCCK
    • Amino acids0 to 0

Specifications

Our Abpromise guarantee covers the use of ab50048 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityBiological Activity : Determined by its ability to chemoattract CD34+ dendritic cells using a concentration range of 100.0-1000.0 ng/ml.
  • Applications

    SDS-PAGE

    Functional Studies

  • Purity> 95 % by SDS-PAGE.
    Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General info

  • Alternative names
    • BD 1
    • BD-1
    • BD1
    • beta 1
    • Beta defensin 1
    • Beta-defensin 1
    • DEFB 1
    • DEFB1
    • DEFB1_HUMAN
    • DEFB101
    • Defensin
    • Defensin beta 1
    • Defensin beta 1 preproprotein
    • HBD 1
    • hBD-1
    • HBD1
    • MGC51822
    see all
  • FunctionHas bactericidal activity.
  • Tissue specificityPlasma.
  • Sequence similaritiesBelongs to the beta-defensin family.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Active human beta Defensin 1 full length protein (ab50048)

ab50048 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. Neither of these proteins are tagged. Both ab50048 and ab50058 both contain a six-cysteine motif that forms three intra-molecular disulfide bonds. I hope this helps, please let me know if you need any additional information...

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Thank you for sending along the dot blots and additional information. We really appreciate the extra troubleshootingeffort.

Here are my thoughts:

1. In general it looks like the antibodies are able to detect Defensin in the chorioam...

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Thank you for contacting Abcam Technical Team and for taking the time to provide some useful details of the experiments. I am very sorry to hear that your customer is are having problems with 8 of our products.  Special thanks for collecting the troubl...

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