Active human Caspase 5 full length protein (ab52109)

Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • SpeciesHuman
    • Amino acids0 to 0

Specifications

Our Abpromise guarantee covers the use of ab52109 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activitySPECIFIC ACTIVITY: 5000 units/mg
  • Applications

    SDS-PAGE

    Functional Studies

  • Purity> 95 % by SDS-PAGE.

  • FormLyophilised
  • Additional Notes


    Active caspase-5 is useful in studying enzyme regulation, determining target substrates, screening caspase inhibitors, or as a positive control in caspase activity assays. Recommend using 1 unit/assay for analyzing caspase activity.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 15% Glycerol, PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • ReconstitutionReconstitute to 1 unit per µl in PBS containing 15% glycerol. Lyophilized caspase-5 is stable for 1 year at –70oC. Following reconstitution, the enzyme should be aliquoted and immediately stored at –70oC.

General info

  • Alternative names
    • Apoptosis related cysteine protease
    • CASP-5
    • CASP5
    • CASP5_HUMAN
    • Caspase-5 subunit p10
    • ICE(rel)-III
    • ICERELIII
    • ICH 3
    • ICH 3 protease
    • Protease ICH-3
    • Protease TY
    • TY
    • TY protease
    see all
  • FunctionMediator of programmed cell death (apoptosis).
  • Tissue specificityExpressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle.
  • Sequence similaritiesBelongs to the peptidase C14A family.
    Contains 1 CARD domain.
  • Post-translational
    modifications
    The two subunits are derived from the precursor sequence by an autocatalytic mechanism.
  • Information by UniProt

References for Active human Caspase 5 full length protein (ab52109)

ab52109 has not yet been referenced specifically in any publications.

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