Active human FGF5 full length protein (ab50229)

Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceMAWAHGEKRL APKGQPGPAA TDRNPIGSSS RQSSSSAMSS SSASSSPAAS LGSQGSGLEQ SSFQWSPSGR RTGSLYCRVG IGFHLQIYPD GKVNGSHEAN MLSVLEIFAV SQGIVGIRGV FSNKFLAMSK KGKLHASAKF TDDCKFRERF QENSYNTYAS AIHRTEKTGR EWYVALNKRG KAKRGCSPRV KPQHISTHFL PRFKQSEQPE LSFTVTVPEK KNPPSPIKSK IPLSAPRKNT NSVKYRLKFR FG
    • Amino acids0 to 0

Specifications

Our Abpromise guarantee covers the use of ab50229 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Purity> 95 % by SDS-PAGE.
    Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • ReconstitutionCentrifuge the vial prior to opening. Reconstitute in 1x PBS, pH 7.2 to a concentration of 0.5–1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use. Repeated freeze thaw cycles will result in some loss of activity.

General info

  • Alternative names
    • FGF 5
    • FGF-5
    • FGF5
    • FGF5_HUMAN
    • Fibroblast growth factor 5
    • HBGF 5
    • HBGF-5
    • heparin binding growth factor 5
    • Heparin-binding growth factor 5
    • Smag 82
    • Smag-82
    see all
  • FunctionFunctions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.
  • Tissue specificityExpressed in neonatal brain.
  • Sequence similaritiesBelongs to the heparin-binding growth factors family.
  • Developmental stageCan transform NIH 3T3 cells.
  • Cellular localizationSecreted.
  • Target information above from: UniProt accession P12034 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

References for Active human FGF5 full length protein (ab50229)

ab50229 has not yet been referenced specifically in any publications.

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