Overview

  • Product name
    Active human RP105 peptide

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab47675 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    The peptide is used for blocking the activity of RP105 antibody (ab45430)
  • Applications

    Western blot

    Blocking - Blocking peptide for Anti-RP105 antibody (ab45430)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • CD180
    • CD180 antigen
    • CD180_HUMAN
    • F630107B15
    • LY64
    • Ly78
    • Lymphocyte antigen 64
    • lymphocyte antigen 64 radioprotective 105kDa
    • lymphocyte antigen-64, radioprotective, 105kDa
    • MGC126233
    • MGC126234
    • Radioprotective 105 kDa protein
    • RP105
    see all
  • Function
    May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells.
  • Tissue specificity
    Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells.
  • Sequence similarities
    Belongs to the Toll-like receptor family.
    Contains 19 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
  • Cellular localization
    Cell membrane.
  • Information by UniProt

References

ab47675 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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