Active human STK25 full length protein (ab125588)

Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected sf9 cells
  • Amino Acid Sequence
    • AccessionO00506
    • SpeciesHuman
    • Molecular weight76 kDa including tags
    • Amino acids1 to 426

Specifications

Our Abpromise guarantee covers the use of ab125588 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityThe specific activity of ab125588 was determined to be 11 nmol/min/mg.
  • Applications

    Western blot

    Functional Studies

    SDS-PAGE

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General info

  • Alternative names
    • C86992
    • Serine/threonine kinase 25
    • Serine/threonine kinase 25 (STE20 homolog, yeast)
    • Serine/threonine kinase 25 (STE20 homolog, yeast), isoform CRA_a
    • Serine/threonine kinase 25 (yeast)
    • Serine/threonine protein kinase 25
    • Serine/threonine-protein kinase 25
    • SOK 1
    • SOK-1
    • SOK1
    • Ste20 like kinase
    • Ste20 yeast homolog
    • Ste20-like
    • STE20-like kinase
    • Ste20/oxidant stress response kinase 1
    • Sterile 20 (oxidant stress response kinase 1)
    • Sterile 20/oxidant stress-response kinase 1
    • STK25
    • STK25_HUMAN
    • Yeast Sps1/Ste20 related kinase 1
    • YSK 1
    • YSK1
    see all
  • FunctionOxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration.
  • Tissue specificityUbiquitously expressed. Highest levels are found in testis, large intestine, brain and stomach followed by heart and lung.
  • Sequence similaritiesBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCytoplasm. Golgi apparatus. Localizes to the Golgi apparatus.
  • Information by UniProt

Active human STK25 full length protein images

  • SDS Page analysis of ab125588
  • The specific activity of ab125588 was determined to be 11 nmol/min/mg

References for Active human STK25 full length protein (ab125588)

ab125588 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"