Active human Tollip peptide (ab40023)
Key features and details
- Active: Yes
- Suitable for: Blocking
Description
-
Product name
Active human Tollip peptide
See all Tollip proteins and peptides -
Biological activity
Blocking the activity of TOLLIP antibody. -
Animal free
No -
Nature
Synthetic -
-
Species
Human
-
Associated products
-
Corresponding Antibody
Specifications
Our Abpromise guarantee covers the use of ab40023 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
Blocking - Blocking peptide for Anti-Tollip antibody (ab37155)
-
Form
Liquid -
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSAThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
-
Alternative names
- Adapter protein
- FLJ33531
- IL 1RAcPIP
see all -
Function
Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity. -
Sequence similarities
Belongs to the tollip family.
Contains 1 C2 domain.
Contains 1 CUE domain. -
Post-translational
modificationsPhosphorylated by IRAK1 upon stimulation by IL-1 or microbial products. -
Cellular localization
Cytoplasm. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
Datasheet download
References (0)
ab40023 has not yet been referenced specifically in any publications.