Active mouse IL13 full length protein (ab51919)

Overview

Description

  • NatureRecombinant
  • SourceE. coli
  • Amino Acid Sequence
    • SpeciesMouse
    • Amino acids0 to 0

Specifications

Our Abpromise guarantee covers the use of ab51919 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity

    The ED50 as determined by the dose-dependent stimulation of the proliferation of TF-1 cells was < 4.0 ng/ml, corresponding to a specific activity of > 2.5 x 105 units/mg.

  • Applications

    Functional Studies

    SDS-PAGE

  • Purity> 95 % by SDS-PAGE.
    >98% by SDS-PAGE and HPLC analysis.
  • FormLyophilised
  • Additional NotesThe reconstituted solution can be diluted into other aqueous buffers and stored at 4°C for 1 week or at –20°C for future use.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10mM Sodium citrate, pH 4.0
    Endotoxin level is <0.1 ng per µg of IL-13.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • ReconstitutionCentrifuge the vial prior to opening. Reconstitute in sterile distilled water to a concentration of 0.1-1.0 µg/µl (Note: Slow to dissolve).

General info

  • Alternative names
    • Allergic rhinitis
    • ALRH
    • BHR1
    • Bronchial hyperresponsiveness 1 (bronchial asthma)
    • IL 13
    • IL-13
    • Il13
    • IL13_HUMAN
    • Interleukin 13
    • Interleukin-13
    • MGC116786
    • MGC116788
    • MGC116789
    • NC30
    • P600
    see all
  • FunctionCytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.
  • Involvement in diseaseDefects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:607154]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.
  • Sequence similaritiesBelongs to the IL-4/IL-13 family.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Active mouse IL13 full length protein (ab51919)

ab51919 has not yet been referenced specifically in any publications.

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