Active mouse Urokinase full length protein (ab92641)

Overview

Description

  • NatureRecombinant
  • SourceInsect cells
  • Amino Acid Sequence
    • AccessionP06869
    • SpeciesMouse
    • Amino acids21 to 433

Specifications

Our Abpromise guarantee covers the use of ab92641 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    ELISA

    SDS-PAGE

  • Purity> 95 % by SDS-PAGE.
    ab92641 is > 98% pure by SDS-PAGE.
  • FormLiquid
  • Additional NotesSpectrophotometric Data: Ultraviolet: Absorbance (280nm) = 0.9 epsilon 0.1% = 1.36


    ab92641 demonstrates preferential binding to mouse uPA over Human uPA coated on an ELISA plate.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.1M Sodium chloride, 0.05M Sodium acetate, 1mM EDTA, pH 5.0

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General info

  • Alternative names
    • ATF
    • ATF uPA
    • BDPLT5
    • OTTHUMP00000019849
    • Plasminogen activator
    • Plasminogen activator urinary
    • Plasminogen activator urokinase
    • PLAU
    • QPD
    • u PA
    • U plasminogen activator
    • u-PA
    • U-plasminogen activator
    • UPA
    • URK
    • UROK_HUMAN
    • Urokinase plasminogen activator
    • Urokinase type plasminogen activator
    • Urokinase type plasminogen activator precursor
    • Urokinase-type plasminogen activator chain B
    see all
  • FunctionSpecifically cleave the zymogen plasminogen to form the active enzyme plasmin.
  • Tissue specificityExpressed in the prostate gland and prostate cancers.
  • Sequence similaritiesBelongs to the peptidase S1 family.
    Contains 1 EGF-like domain.
    Contains 1 kringle domain.
    Contains 1 peptidase S1 domain.
  • Post-translational
    modifications
    Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding.
  • Cellular localizationSecreted.
  • Target information above from: UniProt accession P00749 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Active mouse Urokinase full length protein images

  • 12% SDS-PAGE
    Lane 1: Urokinase (5 ug) Reduced
    Lane 2: Urokinase + CPAI (20 ug) Reduced
    Lane 3: Urokinase (5 ug) Non-reduced
    Lane 4: Urokinase + CPAI (20 ug) Non-reduced
    Lane 5: Prestained Standard

References for Active mouse Urokinase full length protein (ab92641)

ab92641 has not yet been referenced specifically in any publications.

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