Active SARS Nucleocapsid Protein protein fragment (ab43030)
- Product nameActive SARS Nucleocapsid Protein protein fragmentSee all SARS Nucleocapsid Protein proteins and peptides ...
- SourceE. coli
- Amino Acid Sequence
- SequenceL DDKDPQFKDN VILLNKHIDA YKTFPPTEPK KDKKKKTDEA QPLPQRQKKQ
- Amino acids340 to 390
Our Abpromise guarantee covers the use of ab43030 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- Biological activityImmunoreactive with sera of SARS infected individuals.
- Purity> 95
% by SDS-PAGE.
Sepharose derived purification.
- Concentration information loading...
Preparation and Storage
- Stability and Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Constituents: 50% Glycerol, 60mM Sodium chloride, 50mM Tris HCl
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- N structural protein
- Nucleocapsid protein
- Protein N
- SARS coronavirus N protein
- SARS CoV
- Severe acute respiratory syndrome
- RelevanceSevere Acute Respiratory Syndrome (SARS), an emerging disease characterized by atypical pneumonia, has recently been attributed to a novel coronavirus (SARS-CoV). SARS is caused by a human coronavirus, which are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics. The nucleocapsid protein of SARS shares little homology with nucleocapsid proteins of other members of the coronavirus family. Nucleocapsid proteins of other coronavirus have been reported to be involved in forming the viral core and also in the packaging and transcription of the viral RNA.
- Cellular localizationInside the virion, complexed with the viral RNA. May be associated with cellular membranes where it participates in viral RNA synthesis and virus budding.
References for Active SARS Nucleocapsid Protein protein fragment (ab43030)
ab43030 has not yet been referenced specifically in any publications.