Anti-ALK-7 antibody - N-terminal (ab77051)
Key features and details
- Rabbit polyclonal to ALK-7 - N-terminal
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ALK-7 antibody - N-terminal
See all ALK-7 primary antibodies -
Description
Rabbit polyclonal to ALK-7 - N-terminal -
Host species
Rabbit -
Specificity
ab77051 is predicted to have no cross-reactivity to ACVR1 or ACVR1B. -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human ALK-7 (N terminal). 15 aa in length. NP_001096.
(Peptide available asab166744) -
Positive control
- WB: Human placenta tissue lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab77051 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 55 kDa.
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Notes |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 55 kDa. |
Target
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Function
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis. -
Tissue specificity
Present in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy. -
Sequence similarities
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Contains 1 GS domain.
Contains 1 protein kinase domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 130399 Human
- Omim: 608981 Human
- SwissProt: Q8NER5 Human
- Unigene: 562901 Human
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Alternative names
- Activin A receptor, type IC antibody
- Activin receptor like kinase 7 antibody
- Activin receptor type 1C precursor antibody
see all
Images
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Lane 1 : Anti-ALK-7 antibody - N-terminal (ab77051) at 1 µg/ml
Lane 2 : Anti-ALK-7 antibody - N-terminal (ab77051) at 2 µg/ml
All lanes : Human placenta lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 55 kDa
Observed band size: 60 kDa why is the actual band size different from the predicted?
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab77051 has not yet been referenced specifically in any publications.