Anti-Activin A Receptor Type IC antibody (ab77051)

Overview

  • Product nameAnti-Activin A Receptor Type IC antibody
    See all Activin A Receptor Type IC primary antibodies
  • Description
    Rabbit polyclonal to Activin A Receptor Type IC
  • Specificityab77051 is predicted to have no cross-reactivity to ACVR1 or ACVR1B.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic 15 amino acid peptide from near the N terminus of Human Activin A Receptor Type IC (NP_001096).

  • Positive control
    • Human placenta tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab77051 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 55 kDa.Can be blocked with Activin A Receptor Type IC peptide (ab166744).

Target

  • FunctionSerine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
  • Tissue specificityPresent in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy.
  • Sequence similaritiesBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 GS domain.
    Contains 1 protein kinase domain.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activin A receptor, type IC antibody
    • Activin receptor like kinase 7 antibody
    • Activin receptor type 1C precursor antibody
    • Activin receptor type IC antibody
    • Activin receptor type-1C antibody
    • Activin receptor-like kinase 7 antibody
    • ACTR IC antibody
    • ACTR-IC antibody
    • ACTRIC antibody
    • ACV1C_HUMAN antibody
    • Acvr1c antibody
    • ACVRLK7 antibody
    • ALK 7 antibody
    • ALK-7 antibody
    • ALK7 antibody
    see all

Anti-Activin A Receptor Type IC antibody images

  • Lane 1 : Anti-Activin A Receptor Type IC antibody (ab77051) at 1 µg/ml
    Lane 2 : Anti-Activin A Receptor Type IC antibody (ab77051) at 2 µg/ml

    Lane 1 : Human placenta lysate
    Lane 2 : Human placenta lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 55 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)

References for Anti-Activin A Receptor Type IC antibody (ab77051)

ab77051 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab77051.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"