Anti-Activin Receptor Type IA antibody (ab60158)


  • Product nameAnti-Activin Receptor Type IA antibody
    See all Activin Receptor Type IA primary antibodies
  • Description
    Rabbit polyclonal to Activin Receptor Type IA
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide from the center region of human Activin Receptor Type IA conjugated to KLH

  • Positive control
    • Mouse brain tissue lysate



Our Abpromise guarantee covers the use of ab60158 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 57 kDa (predicted molecular weight: 57 kDa).


  • FunctionOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis.
  • Tissue specificityExpressed in normal parenchymal cells, endothelial cells, fibroblasts and tumor-derived epithelial cells.
  • Involvement in diseaseDefects in ACVR1 are a cause of fibrodysplasia ossificans progressiva (FOP) [MIM:135100]. FOP is a rare autosomal dominant disorder of skeletal malformations and progressive extraskeletal ossification. Heterotopic ossification in FOP begins in childhood and can be induced by trauma or may occur without warning. Bone formation is episodic and progressive, leading to extra-articular ankylosis of all major joints of the axial and appendicular skeleton, rendering movement impossible.
  • Sequence similaritiesBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 GS domain.
    Contains 1 protein kinase domain.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activin A receptor type I antibody
    • Activin A receptor type II like kinase 2 antibody
    • Activin receptor type I antibody
    • Activin receptor type-1 antibody
    • Activin receptor-like kinase 2 antibody
    • ACTR-I antibody
    • ACTRI antibody
    • Acvr1 antibody
    • ACVR1_HUMAN antibody
    • ACVR1A antibody
    • ACVRLK2 antibody
    • ALK 2 antibody
    • ALK-2 antibody
    • ALK2 antibody
    • FOP antibody
    • Hydroxyalkyl protein kinase antibody
    • Serine/threonine-protein kinase receptor R1 antibody
    • SKR1 antibody
    • TGF-B superfamily receptor type I antibody
    • TGFB superfamily receptor type I antibody
    • TSR-I antibody
    • TSRI antibody
    see all

Anti-Activin Receptor Type IA antibody images

  • Anti-Activin Receptor Type IA antibody (ab60158) at 1/100 dilution + mouse brain lysate

    Predicted band size : 57 kDa
    Observed band size : 57 kDa

References for Anti-Activin Receptor Type IA antibody (ab60158)

ab60158 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab60158.
Please use the links above to contact us or submit feedback about this product.