Anti-Activin Receptor Type IIA antibody [MM0058-6J16] (ab78412)

Overview

  • Product nameAnti-Activin Receptor Type IIA antibody [MM0058-6J16]
    See all Activin Receptor Type IIA primary antibodies
  • Description
    Mouse monoclonal [MM0058-6J16] to Activin Receptor Type IIA
  • SpecificitySpecific for human Activin RIIA. No cross reactivity was found to hActivin RI and RIIB.
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant Activin RIIA extra cellular domain

Properties

Applications

Our Abpromise guarantee covers the use of ab78412 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Predicted molecular weight: 58 kDa.
IHC-P 1/50 - 1/100.

Target

  • FunctionOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
  • Sequence similaritiesBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 protein kinase domain.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activin A receptor type IIA antibody
    • Activin receptor type 2A antibody
    • Activin receptor type IIA antibody
    • Activin receptor type-2A antibody
    • ACTR 2 antibody
    • ACTR IIA antibody
    • ACTR-IIA antibody
    • ACTR2 antibody
    • ACTRII antibody
    • ACTRIIA antibody
    • Acvr 2 antibody
    • Acvr 2A antibody
    • Acvr2 antibody
    • ACVR2A antibody
    • AVR2A_HUMAN antibody
    • OTTHUMP00000197918 antibody
    see all

Anti-Activin Receptor Type IIA antibody [MM0058-6J16] images

  • ab78412 at 1/100 dilution staining Activin Receptor Type IIA in human placental tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin embedded sections).

References for Anti-Activin Receptor Type IIA antibody [MM0058-6J16] (ab78412)

ab78412 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. The negative control was a no primary of the same placental tissue, rather than a tissue that does not express the receptor.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"