The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 48 kDa).
RelevanceACTR3B plays a role in the organization of the actin cytoskeleton and may function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization. Together with an activating nucleation-promoting factor (NPF) it mediates the formation of branched actin networks. ACTR3B may also decrease the metastatic potential of tumors.