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ab1997 has been referenced in 38 publications.

  • Lu Y  et al. Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells. FASEB J 31:1382-1397 (2017). WB . PubMed: 28034848
  • Jiao T  et al. Role of MicroRNA-103a Targeting ADAM10 in Abdominal Aortic Aneurysm. Biomed Res Int 2017:9645874 (2017). WB, IHC ; Mouse . PubMed: 28357407
  • Hurst LA  et al. TNFa drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling. Nat Commun 8:14079 (2017). WB . PubMed: 28084316
  • Grieve AG  et al. Phosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling. Elife 6:N/A (2017). PubMed: 28432785
  • Park TS  et al. Humulus japonicus inhibits the progression of Alzheimer's disease in a APP/PS1 transgenic mouse model. Int J Mol Med 39:21-30 (2017). PubMed: 28004107
  • Liu B  et al. MAZ mediates the cross-talk between CT-1 and NOTCH1 signaling during gliogenesis. Sci Rep 6:21534 (2016). PubMed: 26867947
  • Jaako K  et al. Prolyl endopeptidase is involved in the degradation of neural cell adhesion molecules in vitro. J Cell Sci 129:3792-3802 (2016). PubMed: 27566163
  • Cai Z  et al. Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration. Cell Res N/A:N/A (2016). PubMed: 27444869
  • Yan X  et al. Ginsenoside Rd. promotes non-amyloidogenic pathway of amyloid precursor protein processing by regulating phosphorylation of estrogen receptor alpha. Life Sci N/A:N/A (2016). PubMed: 27825720
  • Sooy K  et al. Cognitive and Disease-Modifying Effects of 11ß-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer's Disease. Endocrinology 156:4592-603 (2015). WB ; Mouse . PubMed: 26305888
  • Richter E  et al. A multi-omics approach identifies key hubs associated with cell type-specific responses of airway epithelial cells to staphylococcal alpha-toxin. PLoS One 10:e0122089 (2015). WB . PubMed: 25816343
  • Leoni G  et al. Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair. J Clin Invest 125:1215-27 (2015). PubMed: 25664854
  • Dombernowsky SL  et al. The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17. Nat Commun 6:7518 (2015). PubMed: 26108729
  • Chen AC  et al. Physical and functional interaction between the a- and ?-secretases: A new model of regulated intramembrane proteolysis. J Cell Biol 211:1157-76 (2015). ICC . PubMed: 26694839
  • Xu JX  et al. Polycystin-1 and Ga12 regulate the cleavage of E-cadherin in kidney epithelial cells. Physiol Genomics 47:24-32 (2015). PubMed: 25492927
  • Wang J  et al. TRPC6 specifically interacts with APP to inhibit its cleavage by ?-secretase and reduce Aß production. Nat Commun 6:8876 (2015). PubMed: 26581893
  • Morancho B  et al. Role of ADAM17 in the non-cell autonomous effects of oncogene-induced senescence. Breast Cancer Res 17:106 (2015). PubMed: 26260680
  • Shitomi Y  et al. ADAM10 controls collagen signaling and cell migration on collagen by shedding the ectodomain of discoidin domain receptor 1 (DDR1). Mol Biol Cell 26:659-73 (2015). PubMed: 25540428
  • Gooden MJ  et al. Elevated serum CXCL16 is an independent predictor of poor survival in ovarian cancer and may reflect pro-metastatic ADAM protease activity. Br J Cancer 110:1535-44 (2014). PubMed: 24518602
  • Raikwar NS  et al. N-terminal cleavage and release of the ectodomain of Flt1 is mediated via ADAM10 and ADAM 17 and regulated by VEGFR2 and the Flt1 intracellular domain. PLoS One 9:e112794 (2014). PubMed: 25387128
  • Guo LY  et al. Iron increases APP translation and amyloid-beta production in the retina. Exp Eye Res 129:31-7 (2014). WB ; Human . PubMed: 25456519
  • Schiffmacher AT  et al. Cadherin-6B is proteolytically processed during epithelial-to-mesenchymal transitions of the cranial neural crest. Mol Biol Cell 25:41-54 (2014). IHC . PubMed: 24196837
  • Ji YJ  et al. EphrinB2 affects apical constriction in Xenopus embryos and is regulated by ADAM10 and flotillin-1. Nat Commun 5:3516 (2014). PubMed: 24662724
  • Ma J  et al. Noncanonical activation of Notch1 protein by membrane type 1 matrix metalloproteinase (MT1-MMP) controls melanoma cell proliferation. J Biol Chem 289:8442-9 (2014). WB ; Human . PubMed: 24492617
  • Romi E  et al. ADAM metalloproteases promote a developmental switch in responsiveness to the axonal repellant Sema3A. Nat Commun 5:4058 (2014). PubMed: 24898499
  • Klingener M  et al. N-cadherin promotes recruitment and migration of neural progenitor cells from the SVZ neural stem cell niche into demyelinated lesions. J Neurosci 34:9590-606 (2014). WB, ICC, IHC . PubMed: 25031401
  • Wilkinson AC  et al. RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction. Cell Rep 3:116-27 (2013). WB ; Human . PubMed: 23352661
  • Luo L  et al. Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. Elife 2:e00324 (2013). IHC-Fr ; Mouse . PubMed: 23795287
  • Doberstein K  et al. The transcription factor PAX2 regulates ADAM10 expression in renal cell carcinoma. Carcinogenesis : (2011). PubMed: 21880579
  • Thorp E  et al. Shedding of the Mer Tyrosine Kinase Receptor Is Mediated by ADAM17 Protein through a Pathway Involving Reactive Oxygen Species, Protein Kinase C{delta}, and p38 Mitogen-activated Protein Kinase (MAPK). J Biol Chem 286:33335-44 (2011). PubMed: 21828049
  • Zhao S  et al. Proteases and sFlt-1 release in the human placenta. Placenta 31:512-8 (2010). PubMed: 20434767
  • Rabquer BJ  et al. Junctional Adhesion Molecule-C Is a Soluble Mediator of Angiogenesis. J Immunol : (2010). WB ; Human . PubMed: 20592283
  • Donmez G  et al. SIRT1 Suppresses beta-Amyloid Production by Activating the alpha-Secretase Gene ADAM10. Cell 142:320-332 (2010). WB ; Mouse . PubMed: 20655472
  • Schelter F  et al. A Disintegrin and Metalloproteinase-10 (ADAM-10) Mediates DN30 Antibody-induced Shedding of the Met Surface Receptor. J Biol Chem 285:26335-40 (2010). WB ; Human . PubMed: 20554517
  • Amadio M  et al. nELAV proteins alteration in Alzheimer's disease brain: a novel putative target for amyloid-beta reverberating on AbetaPP processing. J Alzheimers Dis 16:409-19 (2009). WB ; Human . PubMed: 19221430
  • Xu D  et al. Tetraspanin12 regulates ADAM10-dependent cleavage of amyloid precursor protein. FASEB J 23:3674-81 (2009). PubMed: 19587294
  • Dittmer A  et al. Human mesenchymal stem cells induce E-cadherin degradation in breast carcinoma spheroids by activating ADAM10. Cell Mol Life Sci 66:3053-65 (2009). WB ; Human . PubMed: 19603142
  • Hakulinen J & Keski-Oja J ADAM10-mediated release of complement membrane cofactor protein during apoptosis of epithelial cells. J Biol Chem 281:21369-76 (2006). PubMed: 16735514

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