Anti-ADAM17 antibody (ab39162)

ab39162 has been referenced in 13 publications.

• Hedemann N  et al. ADAM17 inhibition enhances platinum efficiency in ovarian cancer. Oncotarget 9:16043-16058 (2018). PubMed: 29662625
• Shirakabe K  et al. Mechanistic insights into ectodomain shedding: susceptibility of CADM1 adhesion molecule is determined by alternative splicing and O-glycosylation. Sci Rep 7:46174 (2017). PubMed: 28393893
• Carnuta MG  et al. Dysfunctional high-density lipoproteins have distinct composition, diminished anti-inflammatory potential and discriminate acute coronary syndrome from stable coronary artery disease patients. Sci Rep 7:7295 (2017). PubMed: 28779156
• Hurst LA  et al. TNFa drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling. Nat Commun 8:14079 (2017). WB . PubMed: 28084316
• Bolino A  et al. Niacin-mediated Tace activation ameliorates CMT neuropathies with focal hypermyelination. EMBO Mol Med 8:1438-1454 (2016). PubMed: 27799291
• Chapnick DA  et al. A biosensor for the activity of the "sheddase" TACE (ADAM17) reveals novel and cell type-specific mechanisms of TACE activation. Sci Signal 8:rs1 (2015). PubMed: 25714465
• Dombernowsky SL  et al. The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17. Nat Commun 6:7518 (2015). IP . PubMed: 26108729
• Morancho B  et al. Role of ADAM17 in the non-cell autonomous effects of oncogene-induced senescence. Breast Cancer Res 17:106 (2015). PubMed: 26260680
• Huang Y  et al. Targeting the sheddase activity of ADAM17 by an anti-ADAM17 antibody D1(A12) inhibits head and neck squamous cell carcinoma cell proliferation and motility via blockage of bradykinin induced HERs transactivation. Int J Biol Sci 10:702-14 (2014). PubMed: 25013379
• Fleck D  et al. Dual cleavage of neuregulin 1 type III by BACE1 and ADAM17 liberates its EGF-like domain and allows paracrine signaling. J Neurosci 33:7856-69 (2013). PubMed: 23637177
• Rothhaar TL  et al. Plasmalogens Inhibit APP Processing by Directly Affecting ?-Secretase Activity in Alzheimer's Disease. ScientificWorldJournal 2012:141240 (2012). WB ; Human . PubMed: 22547976
• Marballi K  et al. Differential neuregulin 1 cleavage in the prefrontal cortex and hippocampus in schizophrenia and bipolar disorder: preliminary findings. PLoS One 7:e36431 (2012). WB ; Human . PubMed: 22590542
• Grimm MO  et al. Docosahexaenoic acid reduces amyloid beta production via multiple pleiotropic mechanisms. J Biol Chem 286:14028-39 (2011). WB ; Human . PubMed: 21324907