Overview

  • Product nameAnti-ADAM2 antibody
    See all ADAM2 primary antibodies
  • Description
    Mouse monoclonal to ADAM2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment: RLDPFFKQQA VCGNAKLEAG EECDCGTEQD CALIGETCCD IATCRFKAGS NCAEGPCCEN CLFMSKERMC RPSFEECDLP EYCNGSSASC PENHYVQTGH , corresponding to amino acids 376-476 of Human ADAM2

Properties

Applications

Our Abpromise guarantee covers the use of ab55028 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionSperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.
    • Tissue specificityExpressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues.
    • Sequence similaritiesContains 1 disintegrin domain.
      Contains 1 EGF-like domain.
      Contains 1 peptidase M12B domain.
    • DomainA tripeptide motif (FEE) within disintegrin-like domain could be involved in the binding to egg integrin receptor and thus could mediate sperm/egg binding.
    • Post-translational
      modifications
      The prodomain and the metalloprotease domain are cleaved during the epididymal maturation of the spermatozoa.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • A disintegrin and metalloproteinase domain 2 antibody
      • ADAM 2 antibody
      • ADAM metallopeptidase domain 2 antibody
      • Adam2 antibody
      • ADAM2_HUMAN antibody
      • AI323749 antibody
      • Cancer/testis antigen 15 antibody
      • CRYN1 antibody
      • CRYN2 antibody
      • CT15 antibody
      • Disintegrin and metalloproteinase domain-containing protein 2 antibody
      • Fertilin beta antibody
      • Fertilin subunit beta antibody
      • Ftnb antibody
      • PH 30 antibody
      • PH 30b antibody
      • PH-30 antibody
      • PH30 antibody
      • Ph30 beta antibody
      • PH30-beta antibody
      see all

    Anti-ADAM2 antibody images

    • Western blot against tagged recombinant protein immunogen using ab55028 ADAM2 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    References for Anti-ADAM2 antibody (ab55028)

    ab55028 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"