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Products:Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> MMP
Overview
Product name
Anti-ADAM9 antibody - Carboxyterminal end
See all ADAM9 products (9) ...
Description
Rabbit polyclonal to ADAM9 - Carboxyterminal end
Specificity
This antibody is specific for C terminal domain of ADAM9. It does not react with other ADAMs. We have a range of domain specific antibodies for this target. For a full list please see all ADAM9 antibodies.
Tested applications
Cross reactivity
Reacts with
Rat, Human, Pig
Predicted to work with
Mouse
Immunogen
Synthetic peptide based on the carboxyterminal end of human ADAM9.
(Peptide available as ab41162.)
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.01% Sodium Azide
Constituents: 50% Glycerol
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Metalloprotease >> ADAMs
Cancer >> Invasion/microenvironment >> ECM >> Extracellular matrix >> ADAM protein family
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> ADAM Protein Family
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> MMP
Applications
Show applications key
Our Abpromise guarantee covers the use of ab28210 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
Application notes
WB: 1/1000 when using colorimetric substrates such as BCIP/NBT, and 1/5000 for chemiluminescent substrates. Detects a band of approximately 75 kDa (predicted molecular weight: 91 kDa). EDTA/EGTA treatment of tissues or lysates is required to see latent zymogen. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
ADAM9 encodes disintegrin and metalloprotease (ADAM) domain 9, which is a member of the ADAM protein family. Members of this family are membrane- anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell- cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The member encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
Cellular localization
Isoform 1: Cell membrane; single-pass type I membrane protein. Isoform 2: Secreted protein.
Alternative names
- A disintegrin and metalloproteinase domain 9 antibody
- ADAM 9 antibody
- ADAM metallopeptidase domain 9 antibody
see all
Database links
- Entrez Gene: 8754 Human
- Entrez Gene: 11502 Mouse
- Entrez Gene: 397344 Pig
- Entrez Gene: 290834 Rat
- Omim: 602713 Human
- SwissProt: B7ZLN7 Human
- SwissProt: Q10718 Human
- SwissProt: Q13443 Human
see all
Protocols
References for Anti-ADAM9 antibody - Carboxyterminal end (ab28210)
ab28210 has not yet been referenced specifically in any publications.
Publishing research using ab28210? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"