|
|
|
|
|
Product Name
|
ADAM9 antibody - Carboxyterminal end
|
| |
See all ADAM9 antibodies (9)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Rabbit polyclonal to ADAM9 - Carboxyterminal end
|
|
Immunogen
|
Synthetic peptide based on the carboxyterminal end of human ADAM9.
(Peptide available as ab41162.)
|
|
Reacts with
|
Hu, Rat, Pig
|
|
Predicted to react
(species key)
|
Ms (Due to sequence homology)
|
|
Specificity
|
This antibody is specific for C terminal domain of ADAM9. It does not react with other ADAMs.
We have a range of domain specific antibodies for this target. For a full list please see all ADAM9 antibodies.
We have a range of domain specific antibodies for this target. For a full list please see all ADAM9 antibodies
|
|
Tested applications
(see key)
|
WB
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions WB: 1/1000 when using colorimetric substrates such as BCIP/NBT, and 1/5000 for chemiluminescent substrates. Detects a band of approximately 75 kDa (predicted molecular weight: 91 kDa). EDTA/EGTA treatment of tissues or lysates is required to see latent zymogen. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
|
|
Cellular localization
|
Isoform 1: Cell membrane; single-pass type I membrane protein. Isoform 2: Secreted protein.
|
|
Research areas
|
Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Metalloprotease >> ADAMs Cancer >> Invasion/microenvironment >> ECM >> Extracellular matrix >> ADAM protein family Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> ADAM Protein Family Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> MMP
|
|
Relevance
|
ADAM9 encodes disintegrin and metalloprotease (ADAM) domain 9, which is a member of the ADAM protein family. Members of this family are membrane- anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell- cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The member encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
|
|
|
|
|
Database links
|
The links below go to external sites and will open in a new browser window
|
|
Raised in
|
Rabbit
|
|
Clonality
|
Polyclonal
|
|
Isotype
|
IgG
|
|
Purity
|
Immunogen affinity purified
|
|
Storage buffer
|
Preservative: 0.01% Sodium Azide Constituents: 50% Glycerol Material safety datasheets (MSDS) for this product: Glycerol MSDS Sodium Azide MSDS
|
|
Form
|
Liquid
|
|
Concentration
|
1.000 mg/ml
|
|
Storage instructions
|
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ADAM9 antibody - Carboxyterminal end is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
| |
|
Search PubMed (MEDLINE) for references to ADAM9
|
| |
ADAM9 antibody - Carboxyterminal end - more information
|
Customer reviews (feedback) regarding ADAM9 antibody - Carboxyterminal end |
Customer FAQs regarding ADAM9 antibody - Carboxyterminal end |
Protocols for ADAM9 antibody - Carboxyterminal end |
Price and availability of products related to ADAM9 antibody - Carboxyterminal end |
| |
ADAM9 antibody - Carboxyterminal end - related products:
|
|
|
| |
ADAM9 antibody - Carboxyterminal end - other tools:
|
Contact Abcam with a Technical Enquiry about ADAM9 antibody - Carboxyterminal end |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"