Overview

  • Product nameAnti-ADAMDEC1 antibody
    See all ADAMDEC1 primary antibodies
  • Description
    Mouse monoclonal to ADAMDEC1
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 361-471 of Human ADAMDEC1

Properties

Applications

Our Abpromise guarantee covers the use of ab57224 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay play an important role in the control of the immune response and during pregnancy.
    • Tissue specificityExpressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. Predominantly expressed in dendritic cells (DC) of the germinal center. Weakly expressed in monocyte and highly expressed in macrophage. Absent in immature DC.
    • Sequence similaritiesContains 1 disintegrin domain.
      Contains 1 peptidase M12B domain.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • A disintegrin and metalloproteinase domain like protein decysin 1 antibody
      • A disintegrin and metalloproteinase domain-like protein decysin-1 antibody
      • ADAM DEC1 antibody
      • ADAM like decysin 1 antibody
      • ADAM like protein decysin 1 antibody
      • ADAM-like protein decysin-1 antibody
      • ADAMDEC 1 antibody
      • Adamdec1 antibody
      • ADEC1_HUMAN antibody
      • Decysin antibody
      • Disintegrin protease antibody
      • M12.219 antibody
      see all

    Anti-ADAMDEC1 antibody images

    • ADAMDEC1 antibody (ab57224) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human tonsil.
    • Western blot against tagged recombinant protein immunogen using ab57224 ADAMDEC1 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa

    References for Anti-ADAMDEC1 antibody (ab57224)

    This product has been referenced in:
    • Lund J  et al. Evidence for restricted reactivity of ADAMDEC1 with protein substrates and endogenous inhibitors. J Biol Chem 290:6620-9 (2015). WB . Read more (PubMed: 25564618) »
    • Lund J  et al. ADAMDEC1 is a metzincin metalloprotease with dampened proteolytic activity. J Biol Chem 288:21367-75 (2013). WB . Read more (PubMed: 23754285) »

    See all 2 Publications for this product

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    There are currently no Abreviews or Questions for ab57224.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"