Overview

  • Product nameAnti-ADAMTS12 antibody
    See all ADAMTS12 primary antibodies
  • Description
    Chicken polyclonal to ADAMTS12
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Dog, Human, Chimpanzee
  • Immunogen

    Synthetic peptide, corresponding to Internal sequence amino acids 297-446 of Human ADAMTS12.

Properties

Applications

Our Abpromise guarantee covers the use of ab37760 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/2000. Detects a band of approximately 65 kDa (predicted molecular weight: 178 kDa). We recommend using about 2.5 ug of positive control protein in the colorimetric method, and about 10x less for ECL detection.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceThis protein is a disintegrin and metalloproteinase with thrombospondin motifs 12 (ADAMTS12), which is a member of the ADAMTS protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin like domain, and a thrombospondin type 1 (TS 1) motif. Individual members of this family differ in the number of C terminal TS 1 motifs, and some have unique C terminal domains. The enzyme encoded by this gene contains 8 TS 1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion.
    • Cellular localizationSecreted
    • Database links
    • Alternative names
      • A disintegrin and metalloproteinase with thrombospondin motifs 12 antibody
      • A disintegrin like and metalloprotease with thrombospondin type 1 motif 12 antibody
      • ADAM metallopeptidase with thrombospondin type 1 motif 12 antibody
      • ADAM TS 12 antibody

    Anti-ADAMTS12 antibody images

    • Anti-ADAMTS12 antibody (ab37760) at 1/2000 dilution + E. coli derived fusion protein

      Secondary
      HRP conjugated Goat anti IgY at 1/1000 dilution

      Predicted band size : 178 kDa
      Observed band size : 65 kDa (why is the actual band size different from the predicted?)

    References for Anti-ADAMTS12 antibody (ab37760)

    ab37760 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"