Overview

  • Product nameAnti-ADAMTS18 antibody
    See all ADAMTS18 primary antibodies
  • Description
    Rabbit polyclonal to ADAMTS18
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 144-193 (FYQGFIRNDS SSSVAVSTCA GLSGLIRTRK NEFLISPLPQ LLAQEHNYSS) of human ADAMTS18 (NP_955387).

  • Positive control
    • 721_B cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab82672 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 135 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Tissue specificityExpressed in fetal lung, liver, and kidney and in adult brain, prostate, submaxillary gland, and endothelium.
  • Sequence similaritiesContains 1 disintegrin domain.
    Contains 1 peptidase M12B domain.
    Contains 1 PLAC domain.
    Contains 5 TSP type-1 domains.
  • DomainThe conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • Post-translational
    modifications
    The precursor is cleaved by a furin endopeptidase.
  • Cellular localizationSecreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • A disintegrin and metalloproteinase with thrombospondin motifs 18 antibody
    • A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 18 antibody
    • A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 21 antibody
    • ADAM metallopeptidase with thrombospondin type 1 motif 18 antibody
    • ADAM-TS 18 antibody
    • ADAM-TS18 antibody
    • ADAMTS 18 antibody
    • ADAMTS-18 antibody
    • ADAMTS18 antibody
    • ADAMTS21 antibody
    • ATS18_HUMAN antibody
    • Disintegrin and metalloprotease like protein antibody
    • EC 3.4.24. antibody
    • KNO2 antibody
    see all

Anti-ADAMTS18 antibody images

  • Anti-ADAMTS18 antibody (ab82672) at 1 µg/ml + 721_B cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 135 kDa
    Observed band size : 135 kDa
    Additional bands at : 48 kDa. We are unsure as to the identity of these extra bands.

References for Anti-ADAMTS18 antibody (ab82672)

ab82672 has not yet been referenced specifically in any publications.

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