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Storage instructions Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer Preservative: None
Constituents: 2% Sucrose, PBS
Concentration information loading...
Purity Immunogen affinity purified
Purification notes affinity chromatography method
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 135 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Tissue specificity Expressed in fetal lung, liver, and kidney and in adult brain, prostate, submaxillary gland, and endothelium.
Sequence similarities Contains 1 disintegrin domain. Contains 1 peptidase M12B domain. Contains 1 PLAC domain. Contains 5 TSP type-1 domains.
Domain The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
Post-translational modifications The precursor is cleaved by a furin endopeptidase.
Cellular localization Secreted > extracellular space > extracellular matrix.
Information by UniProt
A disintegrin and metalloproteinase with thrombospondin motifs 18 antibody
A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 18 antibody
A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 21 antibody
Anti-ADAMTS18 antibody images
References for Anti-ADAMTS18 antibody (ab82672)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"