Overview

  • Product name
  • Description
    Rabbit polyclonal to ADAT1
  • Tested applications
    Suitable for: IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: YLLHQLQLAA TLKEDSIFVP GTQKGVWKLR RDLIFVFFSS HTPCGDASII PMLEFEDQPC CPVFRNWAHN SSVEASSNLE APGNERKCED PD, corresponding to amino acids 99-190 of Human ADAT1.

  • Positive control
    • Human lymph node tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab122676 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

Target

  • Function
    Specifically deaminates adenosine-37 to inosine in tRNA-Ala.
  • Tissue specificity
    Ubiquitously expressed.
  • Sequence similarities
    Belongs to the ADAT1 family.
    Contains 1 A to I editase domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • ADAT 1 antibody
    • ADAT1 antibody
    • ADAT1_HUMAN antibody
    • Adenosine deaminase acting on tRNA antibody
    • Adenosine deaminase tRNA specific 1 antibody
    • hADAT1 antibody
    • tRNA specific adenosine deaminase 1 antibody
    • tRNA-specific adenosine deaminase 1 antibody
    • tRNA-specific adenosine-37 deaminase antibody
    see all

Images

  • Immunofluorescent staining of Human cell line U-2 OS shows positivity in nucleus but not nucleoli. Recommended concentration of ab122676 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab122676, at 1/20 dilution, staining ADAT1 in paraffin-embedded Human lymph node tissue by Immunohistochemistry.

References

ab122676 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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